ChemicalBook Product Catalog Organic Chemistry Hydrocarbons and derivatives Hydrocarbon nitrification 2-Amino-4-nitrophenol

2-Amino-4-nitrophenol

Product Name2-Amino-4-nitrophenol
CAS99-57-0
MFC6H6N2O3
MW154.12
EINECS202-767-9
MOL File99-57-0.mol

Chemical Properties

Melting point	140-143 °C (lit.)
Boiling point	322.46°C (rough estimate)
Density	1.3617 (estimate)
vapor pressure	0.005Pa at 25℃
refractive index	1.6890 (rough estimate)
Flash point	100 °C
storage temp.	Refrigerator, Under Inert Atmosphere
solubility	DMSO (Slightly), Methanol (Slightly)
pka	6.82±0.22(Predicted)
form	Solid
color	Dark Yellow to Brown
Water Solubility	slightly soluble
BRN	776533
Henry's Law Constant	4.5×10⁶ mol/(m³Pa) at 25℃, HSDB (2015)
Cosmetics Ingredients Functions	HAIR DYEING
Cosmetic Ingredient Review (CIR)	2-Amino-4-nitrophenol (99-57-0)
InChI	1S/C6H6N2O3/c7-5-3-4(8(10)11)1-2-6(5)9/h1-3,9H,7H2
InChIKey	VLZVIIYRNMWPSN-UHFFFAOYSA-N
SMILES	Nc1cc(ccc1O)[N+]([O-])=O
LogP	1.26
CAS DataBase Reference	99-57-0(CAS DataBase Reference)
IARC	3 (Vol. 57) 1993
EPA Substance Registry System	2-Amino-4-nitrophenol (99-57-0)

Safety Information

Hazard Codes	Xi,Xn
Risk Statements	36/37/38-68-43-40-20/21/22
Safety Statements	26-45-36/37/39-36
RIDADR	2811
WGK Germany	2
RTECS	SJ6300000
Hazard Note	Irritant
TSCA	TSCA listed
HS Code	29071990
Storage Class	11 - Combustible Solids
Hazard Classifications	Eye Irrit. 2 Skin Irrit. 2 STOT SE 3
Hazardous Substances Data	99-57-0(Hazardous Substances Data)

MSDS

Provider	Language
3-Amino-4-hydroxynitrobenzene	English
SigmaAldrich	English
ACROS	English
ALFA	English

Usage And Synthesis

Chemical Properties

OCHRE CRYSTALLINE POWDER

Uses

An aromatic constituent found in hair dyes and other cosmetic products with very low levels of mutagenic activity.

Uses

2-Amino-4-nitrophenol is used in preparing some mordant dyes and in some hair dyes.

Definition

ChEBI: 2-Amino-4-nitrophenol is a member of 4-nitrophenols.

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 3, p. 82, 1955
The Journal of Organic Chemistry, 45, p. 4992, 1980 DOI: 10.1021/jo01312a039

General Description

Orange prisms or yellow powder. No odor.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Oxidation of 2-Amino-4-nitrophenol may occur in the presence of air and violent decomposition may occur if 2-Amino-4-nitrophenol is allowed to dry out completely at elevated temperatures. 2-Amino-4-nitrophenol is stable when stored protected from light and under nitrogen for two weeks at temperatures up to 140° F, and storage under nitrogen for up to 24 weeks at room temperature (77° F) should produce no loss of stability. 2-Amino-4-nitrophenol is incompatible with acids, acid chlorides, acid anhydrides, chloroformates and strong oxidizing agents. 2-Amino-4-nitrophenol is also incompatible with iron.

Fire Hazard

Flash point data for 2-Amino-4-nitrophenol are not available. 2-Amino-4-nitrophenol is probably combustible.

Flammability and Explosibility

Non flammable

Purification Methods

Crystallise the phenol from water. [Beilstein 13 IV 896.]

2-Amino-4-nitrophenol

Chemical Properties

Safety Information

MSDS

Usage And Synthesis

Preparation Products And Raw materials

2-Amino-4-nitrophenol Supplier

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