Nucleoside 5′-Diphosphate Kinase has been used in a study to assess inhibition of type I Fc epsilon receptor mediated Ca2+ influx and mediator secretion in rat mucosal mast cells. It has also been used in a study to investigate protein synthesis in rabbit reticulocytes.
Nucleoside 5′-diphosphate kinase has been used in a study to examine a possible intracellular activity of the drug disodium cromoglycate in mast cells. It has also been used in a study to investigate protein synthesis in rabbit reticulocytes.
Nucleoside 5′-diphosphate kinase is a cytosolic enzyme.
Nucleoside 5′-diphosphate kinase from Saccharomyces cerevisiae is found highly expressed in the cytoplasm. It affects DNA synthesis, in part, by binding to Cdc8p.