溶剂绿 7
溶剂绿 7 性质
| 熔点 | 62-63.5 °C(lit.) |
|---|---|
| 沸点 | 171-178 °C10 mm Hg(lit.) |
| 密度 | 2.15 |
| 蒸气压 | 0Pa at 25℃ |
| 闪点 | 250 °C |
| 储存条件 | Keep in dark place,Inert atmosphere,Room temperature |
| 溶解度 | 溶于甲醇，溶解度为0.1g/mL，澄清 |
| 色指数 | 59040 |
| 形态 | 粉末 |
| 酸度系数(pKa) | 7.3, (at 22℃) |
| 颜色 | 粘黄色 |
| 水溶解性 | 300 g/L (25 ºC) |
| 最大波长(λmax) | 403 nm (Buffer pH 4.0); 454 nm (Buffer pH 9.0) |
| 激发峰(Ex)/发射峰(Em) | λex 404, 369 nm; λem 509, 440 nm in HCl 0.1 M; pH 1 |
| Merck | 7954 |
| BRN | 4107272 |
| 主要应用 | 粘合剂; 农用化学品; 氨气传感器; 二氧化碳传感器; 氧传感器; 阴离子表面活性剂传感器; 测量有机粘土聚集体的尺寸; 检测金属表面裂纹/缺陷、检测制冷剂泄漏; 洗涤剂; 修正液; 荧光笔; 墨水; 标记笔; 油漆; 铅笔; 色粉; 化学放大光刻胶; 彩色滤光片; 化学发光材料; 电泳显示（EPD）薄膜材料; 电致发光显示器/材料; 燃料电池; 激光器; 液晶显示器; 发光材料; 纳米颗粒; 论文研究; 光刻胶工艺; 光子离子液体; 土壤介质; 太阳能电池; 溶胶-凝胶材料/工艺/薄膜; 声光致发光; 水示踪剂; 评估木材干燥过程中液态水的流动 |
| 生物领域应用 | Antiperspirants; bath preparations; cleansing products; cosmetics; contact lens; hair dyes; hygiene products/soaps; food products; controlled-release system for proteins; drug delivery; in ophthalmology/retinal surgery; sugar sensors (glucose, fructose, lactose, sucrose); as a substrate for measuring acetylcholinesterase (AChE) activity, carbonic anhydrase activity, esterases activity, β-glucuronidase activity, lipase activity, acidic/alkaline phosphatases activity, pyrophosphatase activity, sucrose phosphorylase (SPO) activity, phosphoglucomutase (PGM) activity; treating cancer, infection, immune/autoimmune disease, mastitis, tonsillitis, tuberculosis |
| 化妆品成分功效 | 着色剂 染发剂 |
| InChIKey | DCEGPALHGHQUSK-UHFFFAOYSA-K |
| SMILES | OC1=C2C(C3=C(C=C4)C(S(=O)([O-])=O)=CC(S(=O)([O-])=O)=C3C=C2)=C4C(S(=O)([O-])=O)=C1.O.[Na+].[Na+].[Na+] |
| LogP | -3.97 at 25℃ |
| CAS 数据库 | 6358-69-6(CAS DataBase Reference) |
| EPA化学物质信息 | C.I. Solvent Green 7 (6358-69-6) |
溶剂绿 7 用途与合成方法
Pyranine is capable of discriminating ranges of cations from the Cu
+
ion, even in competing environment. Pyranine displays a rapid fluorescence response (t
1/2
=1.66 min) towards the Cu
+
ion, and the micromolar detection limit enables the detection of the ion in environmental samples. The observed stoichiometry of complexation between Pyranine and Cu
+
is 2:1.
The pH-sensitive fluorescent indicator Pyranine is studied to determine its usefulness as probes for the living cornea and anterior chamber. Adequate concentrations are reached in the cornea and anterior chamber after topical administration; measurements can be made by fluorophotometry for many hours. The pH is calculated by measuring the ratio of fluorescent intensity at two excitation wavelengths, I463/I404, a measurement which is dependent on pH but independent of the concentration of the fluorophore and other variables which can alter the intensity. In the rabbit eye, Pyranine in the cornea and anterior chamber is observed to undergo easily measurable changes in fluorescent ratios associated with lid closure and contact lens wear, indicating its sensitivity to mild changes in pH.
59572-10-0
6358-69-6
以1,3,6,8-芘四磺酸四钠盐为原料合成溶剂绿7的一般步骤如下：在2000毫升三颈烧瓶中加入1200克浓硫酸，搅拌下加入120克1,3,6,8-芘四磺酸四钠盐，轻微加热以促进完全溶解后，缓慢升温至90°C并维持1小时。反应完成后，用水浴将反应混合物冷却至40°C以下，缓慢滴加480克液体硫磺黑，滴加过程控制在3小时内完成。随后，将反应温度维持在100°C左右继续反应5小时。反应结束后，冷却至室温，将反应混合物倒入720克冰水中，得到粘稠物料，经过滤后干燥滤饼，得到芘四磺酸四钠盐。接下来，将芘四磺酸四钠盐溶于1000毫升水中，转移至2000毫升三口烧瓶中，用氢氧化钠溶液调节至中性，再加入300克片状氢氧化钠。缓慢加热至微沸状态，保持5小时。反应完成后，冷却，先用盐酸调节pH值至7左右，然后加入100克氯化钠搅拌至完全溶解，缓慢沉淀出淡黄色固体。经过滤、干燥，最终得到约245克8-羟基-1,3,6-芘三钠磺酸盐。
参考文献：
[1] Patent: CN105272886, 2016, A. Location in patent: Paragraph 0013; 0026; 0027
安全信息
| 危险品标志 | Xn,Xi |
|---|---|
| 危险类别码 | 36/37/38 |
| 安全说明 | 36/37-37/39-26-36 |
| WGK Germany | 3 |
| RTECS号 | UR2700000 |
| TSCA | TSCA listed |
| 海关编码 | 29089990 |
| 存储类别 | 11 - 可燃固体 |
MSDS信息
溶剂绿 7 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026-09-15 | HY-D0023 | 溶剂绿 7 | 6358-69-6 | 500mg | 325 |
| 2026-09-15 | HY-D0023 | 溶剂绿 7 | 6358-69-6 | 1g | 520 |
