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Protopine Structure

Protopine

Chemical Properties

Melting point 203-205?C
Boiling point 486.8°C (rough estimate)
Density  1.399 (calc)
refractive index  1.5800 (estimate)
storage temp.  Inert atmosphere,2-8°C
Water Solubility  Insoluble in water
solubility  DMSO : 12.5 mg/mL (35.37 mM; Need ultrasonic)
pka 7.86±0.20(Predicted)
form  powder to crystal
color  White to Light gray to Light yellow
LogP 3.760 (est)
NIST Chemistry Reference Protopine(130-86-9)

Safety Information

Safety Statements  24/25
RIDADR  1544
RTECS  VS2800000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29391900
Hazardous Substances Data 130-86-9(Hazardous Substances Data)
Toxicity guinea pig,LD50,intraperitoneal,116mg/kg (116mg/kg),Therapie. Vol. 28, Pg. 767, 1973.

Usage And Synthesis

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