Volvaltrate B

Volvaltrate B is an anticancer agent, iridoid, can be obtained from the root of valerian (Valeriana officinalis). Volvaltrate B is effective against ovarian tumors in female mice. Volvaltrate B has the potential to study cancer[1][2].

[1] Tan YZ, et al. Iridoids from Valeriana jatamansi induce autophagy-associated cell death via the PDK1/Akt/mTOR pathway in HCT116 human colorectal carcinoma cells. Bioorg Chem. 2019 Jun;87:136-141. DOI:10.1016/j.bioorg.2019.03.020
[2] Wang PC, et al. Iridoids and sesquiterpenoids from the roots of Valeriana officinalis. J Nat Prod. 2009 Sep;72(9):1682-5. DOI:10.1021/np9003382