Epifriedelal acetate

Epifriedelanol exhibits antibacterial activities. Epifriedelanol and friedelin possess promising antioxidant activity, and they are active against the two cancer cells (human T4 lymphoblastoid (CEM-SS) and human cervical (HeLa) cancer cells) with IC50 values ranging from 3.54 to145 ug/ml. 3. Epifriedelanol can reduce cellular senescence in human primary cells and may be used to develop dietary supplements or cosmetics that modulate tissue aging or aging-associated diseases.

Epifriedelanol acetate (Compound Ⅲc) is a nature product. Epifriedelanol acetate can be isolated from Pachysandra terminalis Sieb[1].

Antifection

[1] Md Afjalus Siraj, et al. Molecular Docking and Molecular Dynamics Simulation Studies of Triterpenes from Vernonia patula with the Cannabinoid Type 1 Receptor. Int J Mol Sci. 12021 Mar 30;22(7):3595 DOI:10.3390/ijms22073595
[2] Kikuchi T, et al. Studies on the neutral constituents of Pachysandra terminalis Sieb, et Zucc. I. Isolation and characterization of sterols and triterpenes. Yakugaku Zasshi. 1969 Oct;89(10):1358-66. Japanese. DOI:10.1248/yakushi1947.89.10_1358