General method: 3,4,5-trimethoxybenzyl alcohol (1 mmol) was dissolved in anhydrous benzene (15 mL), phosphorus tribromide (0.5 mL) was added and the reaction was stirred at room temperature. Upon completion of the reaction, 3,4,5-trimethoxybenzyl bromide was obtained in quantitative yield by a conventional post-treatment step.
[1] Journal of Steroid Biochemistry and Molecular Biology, 2013, vol. 137, p. 332 - 344
[2] Chemistry - A European Journal, 2015, vol. 21, # 28, p. 10031 - 10038
[3] Medicinal Chemistry Research, 2015, vol. 24, # 8, p. 3143 - 3156
[4] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 5, p. 1630 - 1642
[5] Synthetic Communications, 1987, vol. 17, # 7, p. 877 - 892
