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KU-55933

Basic information Safety Related Supplier
KU-55933 Basic information
KU-55933 Chemical Properties
  • Boiling point:628.0±55.0 °C(Predicted)
  • Density 1.419±0.06 g/cm3(Predicted)
  • storage temp. Desiccate at -20°C
  • form powder
  • pka0.33±0.20(Predicted)
  • color white to beige
Safety Information
  • WGK Germany 3
KU-55933 Usage And Synthesis
  • UsesA potent and specific ATM kinase inhibitor with an IC50 and a Ki of 13 nM and 2.2 nM, respectively.
  • Biological ActivityPotent, selective and competitive ATM kinase inhibitor (K i = 2.2 nM, IC 50 values are 13, 2500, 9300, 16600, > 100000 and > 100000 nM at ATM, DNA-PK, mTOR, PI 3-kinase, PI 4-K and ATR respectively). Decreases viability of MCF-7, A549 and HCT116 cells and decreases p21 CIP1 levels in vitro . Acts as a radio- and chemosensitizer for the treatment of cancer.
KU-55933(587871-26-9)Related Product Information
KU-55933SupplierMore
  • Company Name:Shanghai Boyle Chemical Co., Ltd.
  • Tel:
  • Email:sales@boylechem.com
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  • Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
  • Tel:18930552037 821-50328103-801
  • Email:3bsc@sina.com
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  • Company Name:Chembest Research Laboratories Limited
  • Tel:021-20908456-
  • Email:sales@BioChemBest.com
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  • Company Name:JinYan Chemicals(ShangHai) Co.,Ltd.
  • Tel:13817811078,021-50426030
  • Email:sales@jingyan-chemical.com
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  • Company Name:Chemsky (shanghai) International Co.,Ltd
  • Tel:021-50135380
  • Email:shchemsky@sina.com
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