1-cyanovinyl acetate is a ketene equivalent for use in the Diels-Alder reaction; undergoes other cycloaddition reactions; reacts with nucleophiles and radicals[1].
Poison by inhalation, ingestion, andskin contact. A skin irritant. Whenheated to decomposition it emits toxic fumes of NOx andCN-.
Handling, Storage, and Precautions: highly toxic; use only in a fume hood. Reagent can be absorbed through the skin. Always wear gloves when handling this reagent.
1. Ranganathan, S.; Ranganathan, D.; Mehrotra, A. K. S 1977, 289.
2. Brown, D. S.; Paquette, L. A. JOC 1992, 57, 4512.
3. Nowak, R. M. JOC 1963, 28, 1182.
