Glycolonitrile Chemical Properties
- Melting point:-72°C
- Boiling point:183°C
- Density 1.076 g/mL at 20 °C
- refractive index n
- Flash point:133 °F
- Water Solubility >=10 g/100 mL at 20 ºC
- Stability:Stable, but may react violently with alkalies. Incompatible with strong oxidizing agents.
- CAS DataBase Reference107-16-4(CAS DataBase Reference)
- NIST Chemistry ReferenceAcetonitrile, hydroxy-(107-16-4)
- EPA Substance Registry SystemFormaldehyde cyanohydrin (107-16-4)
Glycolonitrile Usage And Synthesis
- Chemical Propertieslight yellow liquid (typically available as a concentrated
- Chemical PropertiesFormaldehyde cyanohydrin is a colorless, odorless, oily liquid. Sweet taste (very highly toxic; do not test).
- UsesSolvent and organic intermediate.
- Production MethodsGlycolonitrile is the result of reaction between formaldehyde and aqueous sodium cyanide in the presence of mineral acid.
- General DescriptionOdorless colorless oil with a sweetish taste. Used in the manufacture of intermediates in pharmaceutical production, as a component of synthetic resins, as a chemical intermediate for organic compounds, and as a solvent.
- Air & Water ReactionsWater soluble.
- Reactivity ProfileGlycolonitrile may undergo spontaneous and violent decomposition. Traces of alkali (base) promote violent polymerization [Lewis].
- HazardToxic by ingestion, inhalation, and skin absorption.
- Health HazardExtremely toxic, exposure by any route should be avoided; may have fatal consequences; death from asphyxiation may occur similar to that resulting from hydrogen cyanide.
- Fire HazardModerate explosion hazard when exposed to heat or by spontaneous chemical reaction in the presence of alkalies if uninhibited. When heated to decomposition, Glycolonitrile emits highly toxic fumes of cyanide and nitrogen oxides. Unstable, may explode on standing. Hazardous polymerization may occur. avoid the presence of alkalis, and exposure to heat.
- Potential ExposureFormaldehyde cyanohydrin is used in the manufacture of intermediates in pharmaceutical produc tion and as a component of synthetic resins as a chemical intermediate for organic compounds, and as a solvent.
- ShippingUN3276 Nitriles, liquid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required, Potential Inhalation Hazard (Special Provision 5). UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
- IncompatibilitiesIncompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explo sions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, and exposure to heat. Unless stabilized with a weak acid solution, traces of alka lis may cause violent polymerization.
Glycolonitrile Preparation Products And Raw materials
- (3-phenoxyphenyl)glycolonitrile 1-HYDROXY-1-CYCLOHEXANECARBONITRILE 1-BENZYL-4-CYANO-4-HYDROXYPIPERIDINE 1-ACETOXY-1-CYANOETHYLENE 2-HYDROXYPROPIONITRILE 3-CHLOROPHENOXYACETONITRILE Methyl cyanoformate 2-CHLOROPHENOXYACETONITRILE 2-METHOXY-2-PHENYL-3,3,3-TRIFLUOROPROPIONITRILE alpha,alpha-dicyanobenzyl benzoate Glycolonitrile, phenyl- BENZYL CYANOFORMATE BENZOIC ACID CYANOMETHYL ESTER Methoxyacetonitrile Cyanomethyl benzenesulfonate ACETIC ACID 1-CYANO-2-PROPENYL ESTER Ethyl cyanoformate cyanohydrin