Methoxycoronarin D can be isolated from Hedychium coronarium J. Koenig and is a potent inhibitor of NF-κB with an IC50 value of 7.3 μM. Methoxycoronarin D is also a selective inhibitor of COX-1 with an IC50 value of 0.9 μM[1].
References
[1] Endringer D C, et al. Cancer chemoprevention activity of labdane diterpenes from rhizomes of Hedychium coronarium[J]. Revista Brasileira de Farmacognosia, 2014, 24: 408-412.
