trans-2-Decenoic acid is an unsaturated fatty acid found in royal jelly produced from the hypopharyngeal and mandibular gland secretions of honeybees. It is isolated in conjunction with 10-HDA and both demonstrate weak estrogenic activity, inhibiting binding of 17β-estradiol to estrogen receptor β.
clear colorless to pale yellow liquid
(E)-2-Decenoic acid has a peach-orange, slightly waxy aroma. Used in perfumes.
Reported found in lamb, pork fat, black tea and wort.
trans-2-Decenoic acid demonstrates weak estrogenic activity, inhibiting binding of 17β-estradiol (E888000) to estrogen receptor β.
ChEBI: A 2-decenoic acid having its double bond in the trans configuration. It is an intermediate metabolite in the fatty acid synthesis.
[1] KAZU-MICHI SUZUKI. Estrogenic activities of Fatty acids and a sterol isolated from royal jelly.[J]. Evidence-based Complementary and Alternative Medicine, 2008, 5 3: 295-302. DOI:
10.1093/ecam/nem036
