莪术呋喃烯
莪术呋喃烯 性质
| 沸点 | 282.8±40.0℃ (760 Torr) |
|---|---|
| 密度 | 0.982±0.06 g/cm3 (20 ºC 760 Torr) |
| 闪点 | 117.5±14.2℃ |
| 溶解度 | 溶于氯仿 |
| 形态 | 液体 |
| 颜色 | 黄色油状 |
| InChI | InChI=1/C15H20O/c1-6-15(5)8-14-12(11(4)9-16-14)7-13(15)10(2)3/h6,9,13H,1-2,7-8H2,3-5H3/t13-,15+/s3 |
| InChIKey | HICAMHOOTMOHPA-MJZDCSSWNA-N |
| SMILES | O1C2C[C@@](C=C)(C)[C@@H](C(C)=C)CC=2C(C)=C1 |&1:3,7,r| |
| LogP | 3.982 (est) |
莪术呋喃烯 用途与合成方法
GSTA1
Curzerene (0-100 µM; 24-72 hours) indicates that cell inhibition increases in a dose- and time-dependent manner, IC 50 to SPC A1 cells at 24, 48, and 72 h was 403.8 μM, 154.8 µM, and 47.01 µM, respectively. Curzerene (0-100 µM; 48 hours) exhibits a higher percentage of apoptotic and necrotic cells than that of the control group in SPC-A1cells. Curzerene(0-100 µM; 48 hours) indicates that the percentage of cells arrested in the G2/M phase increased from 9.26% in the control group cells to 17.57% in the cells treated with the highest dose. Curzerene (6.25-100 µM; 48 hours) decreases the mRNA expression of GSTA1 in SPC A1 cells. Curzerene (6.25-100 µM; 48 hours) decreases the protein expression of GSTA1 in SPC A1 cells.
Cell Viability Assay
| Cell Line: | SPC-A1 cells |
| Concentration: | 0 µM, 6.25 µM, 12.5 µM, 25 µM, 50 µM, 100 µM |
| Incubation Time: | 24 hours, 48 hours, 72 hours |
| Result: | Inhibited growth of non-small cell lung cancer SPC A1 cells in vitro. |
Apoptosis Analysis
| Cell Line: | SPC-A1 cells |
| Concentration: | 0 µM, 6.25 µM, 12.5 µM, 25 µM, 50 µM, 100 µM |
| Incubation Time: | 48 hours |
| Result: | Induced apoptosis of the cells in a dose-dependent manner. |
Apoptosis Analysis
| Cell Line: | SPC-A1 cells |
| Concentration: | 0 µM, 6.25 µM, 12.5 µM, 25 µM, 50 µM, 100 µM |
| Incubation Time: | 48 hours |
| Result: | Induced G2/M cell cycle arrest of SPC A1 cells. |
RT-PCR
| Cell Line: | SPC-A1 cells |
| Concentration: | 6.25 µM, 25 µM, 100 µM |
| Incubation Time: | 48 hours |
| Result: | Decreased GSTA1 mRNA expression. |
莪术呋喃烯 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026-07-06 | S0970 | 莪术呋喃烯 | 17910-09-7 | 1mg | 1285.83 |
| 2026-07-06 | S0970 | 莪术呋喃烯 | 17910-09-7 | 5mg | 3849.3 |
