alpha-香附酮
alpha-香附酮 性质
| 熔点 | 232 °C |
|---|---|
| 沸点 | 177 °C(Press: 20 Torr) |
| 密度 | 0.9946 g/cm3(Temp: 25 °C) |
| 储存条件 | Sealed in dry,Store in freezer, under -20°C |
| 溶解度 | 可溶于氯仿（少许）、甲醇（少许） |
| 形态 | 油状 |
| 颜色 | 无色至淡黄色 |
| LogP | 4.220 (est) |
alpha-香附酮 用途与合成方法
alpha-香附酮为黄色液体，易溶于甲醇、水，来源于香附，益智仁，莎草科植物香附(莎草) Cyperus rotundus L. 的根茎。
α-Cyperone (alpha-cyperone) 是香附子Cyperus rotundus的主要活性成分，表现出了如抗毒力、抗原毒性和抗菌活性等生物活性。α-Cyperone (alpha-cyperone) 与COX-2、IL-6、Nck-2、Cdc42 和 Rac1 的表达下调有关。
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Human Endogenous Metabolite
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The anti-inflammatory activity of alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2 and IL-6 via the negative regulation of the NFκB pathway in LPS-stimulated RAW 264.7 cells.
alpha-Cyperone (α-Cyperone) binds and interacts with tubulin and is capable of distinctly destabilizing microtubule polymerization. The effect of this interaction could result in reduction of inflammation which would be highly beneficial for treatment of inflammatory diseases such as AD. One microliter of alpha-Cyperone was dissolved in DMSO (1:1 v/v) and it was further diluted in double distilled water (ddH2O) to a final volume of 20 microliter.
药理药效:疏肝解郁，养血调经止痛
alpha-香附酮 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2025-02-05 | HY-N0710 | alpha-香附酮 | 473-08-5 | 5mg | 550 |
| 2025-02-05 | HY-N0710 | alpha-香附酮 | 473-08-5 | 10mg | 853 |
