ChemicalBook > Product Catalog > Pharmaceutical intermediates > Heterocyclic compound > Pyridine compound > Hydroxypyridine > 2-Hydroxypyridine
2-Hydroxypyridine
- Product Name:2-Hydroxypyridine
- CAS:142-08-5
- MF:C5H5NO
- MW:95.1
- EINECS:205-520-3
- Mol File:142-08-5.mol
-
2-Hydroxypyridine Chemical Properties
- Melting point:105-107 °C (lit.)
- Boiling point:280-281 °C (lit.)
- Density 1.39
- refractive index 1.5939 (estimate)
- Flash point:210 °C
- storage temp. Sealed in dry,Room Temperature
- solubility 450g/l
- form Liquid
- pka0.75(at 20℃)
- color Colorless to yellow to brown, darken on storage with no loss of purity
- Water Solubility Soluble in water 450 g/L @ 20°C and ethanol, slightly soluble in benzene and ether.
- BRN 105786
- CAS DataBase Reference142-08-5(CAS DataBase Reference)
- NIST Chemistry Reference2(1H)-Pyridinone(142-08-5)
- EPA Substance Registry System2(1H)-Pyridinone (142-08-5)
- Hazard Codes Xi,Xn,T
- Risk Statements 36/37/38-40-25
- Safety Statements 26-36-37/39-22-45-36/37/39
- RIDADR UN2811
- WGK Germany 3
- RTECS UV1144050
- F 8
- TSCA Yes
- HazardClass 6.1
- PackingGroup III
- HS Code 29333990
- ToxicityLD50 ipr-mus: 410 mg/kg TOXIA6 23,815,85
- Language:EnglishProvider:2-Hydroxypyridine
- Language:EnglishProvider:SigmaAldrich
- Language:EnglishProvider:ACROS
- Language:EnglishProvider:ALFA
2-Hydroxypyridine Usage And Synthesis
- Chemical Propertieswhite to light yellow crystal
- UsesCatalyst for generating β-oxopropyl carbonates from cyclic carbonates and alcohols1 and in the aminolysis of a polyglutamate.2
- DefinitionChEBI: A monohydroxypyridine that is pyridine substituted by a hydroxy group at position 2.
- Safety ProfileModerately toxic by intraperitoneal and intravenous routes. A combustible liquid. When heated to decomposition it emits toxic vapors of NOx.
- Purification MethodsDistil the pyridone under vacuum to remove coloured impurity, then recrystallise from *benzene, CCl4, EtOH or CHCl3/diethyl ether. It can be sublimed under high vacuum. [DePue et al. J Am Chem Soc 107 2131 1985, Beilstein 21/7 V 106.]
2-Hydroxypyridine Preparation Products And Raw materials
- Preparation Products2-Hydroxy-5-bromopyridineDI-2-PYRIDYL THIONOCARBONATEReactive Brilliant Yellow M-7G5-CHLOROPYRIDIN-2(1H)-ONE3,5-DICHLORO-2-PYRIDONEdisodium 4-[[5-(aminocarbonyl)-1-ethyl-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridyl]azo]-6-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]benzene-1,3-disulphonate
- (S)-N-(1-aMino-1-oxobutan-2-yl)-4-chlorobutanaMide Levetiracetam impurity 6 Levetiracetam (R)-2-(2-OXO-PYRROLIDIN-1-YL)-BUTYRAMIDE Levetiracetam impurity 7 LevetiracetaM IMpurity B alpha-Ethyl-2-oxo-1-pyrrolidineacetic acid Levetiracetam impurity 8 Levetiracetam acid (2S)-2-(2-Oxopyrrolidin-1-yl)butanoic acid (R)-(-)-2-AMINOBUTANAMIDE HYDROCHLORIDE, 97% 2,3-Dihydroxypyridine 2-N-BUTOXYPYRIDINE 2,4-Dihydroxypyridine 2-Chloro-6-methoxypyridine 2,6-Dimethoxypyridine 6-HYDROXYPYRIDINE-3-CARBOXYLIC ACID QUINOXALIN-5-AMINE
2-HydroxypyridineSupplierMore
- Company Name:LEWOO PHARMATECH (SHANGHAI) CO.,LTD Gold
- Tel:18116361417
- Email:arita.zhang@lewoopharma.com;miao@lewoopharma.com
- Company Name:J & K SCIENTIFIC LTD.
- Tel:400-666-7788 010-82848833-
- Email:jkinfo@jkchemical.com;market6@jkchemical.com
- Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel:400-660-8290 21-61259100-
- Email:sh@meryer.com
- Company Name:INTATRADE GmbH
- Tel:+49 3493/605464
- Email:sales@intatrade.de
- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:18930552037 821-50328103-801
- Email:3bsc@sina.com
