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DICHLORPHENAMIDE

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DICHLORPHENAMIDE Basic information
DICHLORPHENAMIDE Chemical Properties
Safety Information
DICHLORPHENAMIDE Usage And Synthesis
  • Chemical PropertiesOff-White Solid
  • UsesDiclofenamide is a potent carbonic anhydrase inhibitor. Diclofenamide may provide a therapeutic strategy in the inhibition of the human cytosolic isoforms I and II and transmembrane tumor-associated i soenzymes IX and XII. Diclofenamide has been shown to be is effective in the prevention of episodic weakness in both hypokalemic periodic paralysis (HypoPP) and potassium-sensitive periodic paralysis (PSPP).
  • DefinitionChEBI: A sulfonamide that is benzene-1,3-disulfonamide in which the hydrogens at positions 4 and 5 are substituted by chlorine. An oral carbonic anhydrase inhibitor, it partially suppresses the secretion (inflow) of aqueous humor in the eye and so reduces intraoc lar pressure. It is used for the treatment of glaucoma.
  • brand nameDaranide (Merck).
  • Veterinary Drugs and TreatmentsDichlorphenamide is used for the medical treatment of glaucoma. Because of availability issues and toxic effects associated with systemic therapy, human (and many veterinary) ophthalmologists are using topical carbonic anhydrase inhibitors (e.g., dorzolamide or brinzolamide) in place of acetazolamide, dichlorphenamide or methazolamide.
DICHLORPHENAMIDE Preparation Products And Raw materials
DICHLORPHENAMIDE(120-97-8)Related Product Information
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