Ruthenium Red tetrahydrate

dark red-purple crystalline powder

A blocker of transmembrane Ca²⁺ fluxes (IC₅₀ = 7 µM) that attenuates capsaicin-induced cation channel opening. Inhibits Ca²⁺-induced Ca²⁺ release from ryanodine-sensitive intracellular Ca²⁺ stores. Inhibits K⁺-stimulated catecholamine secretion (IC₅₀ = 6 µM).

Cell permeable: no', 'Primary Target
Blocker of transmembrane Ca2+ fluxes', 'Product does not compete with ATP.', 'Reversible: no', 'Target IC50: 7 μM in blocking transmembrane Ca2+ fluxes; 6 μM inhibiting K+-stimulated catecholamine secretion