卡那霉素 B
卡那霉素 B 性质
| 熔点 | 178-182° (dec) |
|---|---|
| 比旋光度 | D18 +130° (c = 0.5 in water); D21 +114° (c = 0.98 in water) |
| 沸点 | 580.49°C (rough estimate) |
| 密度 | 1.3771 (rough estimate) |
| 折射率 | 1.7600 (estimate) |
| 储存条件 | under inert gas (nitrogen or Argon) at 2–8 °C |
| 溶解度 | 酸水溶液（微溶）、甲醇（微溶、加热、超声处理） |
| 形态 | 固体 |
| 酸度系数(pKa) | 13.07±0.70(Predicted) |
| 颜色 | 晶体 |
| 稳定性 | 吸湿性 |
卡那霉素 B 用途与合成方法
Bekanamycin (Kanamycin B) is a precursor for semisynthetic antibiotics such as Arbekacin and Dibekacin and is generally extracted from the broth of
S. kanamyceticus
.
Bekanamycin (Kanamycin B) in a concentration-dependent fashion reduces reversibly the quantal content of the end-plate potentials while it has no observable effect on the configuration of the extracellularly recorded presynaptic action potential. The reduction in evoked transmitter release produced by Bekanamycin could be antagonized either by increasing the external calcium concentration or by drugs like the aminopyridines which are to greatly enhance transmitter release from motor nerve terminals. Bekanamycin exerts potent inhibitory effects on transmitter release probably by interfering with the influx of calcium that occurs during depolarization of motor nerve terminals.
卡那霉素 B 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024-11-08 | HY-B1174 | 卡那霉素 B | 4696-76-8 | 100mg | 267 |
| 2024-11-08 | HY-B1174 | 卡那霉素 B | 4696-76-8 | 10mM * 1mLin Water | 293 |
