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Cycloleucine

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Cycloleucine Basic information
Cycloleucine Chemical Properties
Safety Information
  • Hazard Codes Xn,Xi
  • Risk Statements 22
  • Safety Statements 22-24/25
  • RIDADR UN 2811 6.1/PG 3
  • WGK Germany 3
  • RTECS GY2625000
  • TSCA Yes
  • HazardClass 6.1
  • PackingGroup III
  • HS Code 29224999
  • Hazardous Substances Data52-52-8(Hazardous Substances Data)
  • ToxicityLD50 oral in rat: 290mg/kg
MSDS
Cycloleucine Usage And Synthesis
  • Chemical PropertiesWHITE TO BEIGE CRYSTALLINE FLAKES OR POWDER
  • UsesNMDA receptor antagonist, inhibits nucleic acid methylation; adrenergic agonist
  • UsesCycloleucine is a synthetic amino acid used in numerous biochemical transport studies
  • DefinitionChEBI: A non-proteinogenic alpha-amino acid that is cyclopentane substituted at position 1 by amino and carboxy groups.
  • Purification MethodsAny Cl -or other anions are removed by stirring with a strong cation exchange resin (Amberlite IR-120), filtering, and washing with distilled H2O until the filtrate is free from the anion. The resin is then stirred overnight with 6N NH4OH, filtered, the filtrate is decolourised (charcoal) and evaporated to dryness in a vacuum. The residue is recrystallised from H2O/EtOH. Also crystallise it from aqueous EtOH. The hydrochloride has m 222-224o(dec). [Neelakantan & Hartung J Org Chem 23 967 1958, Connors & Ross J Chem Soc 2119 1960. O’Donnell et al. Synthesis 127 1984, Beilstein 14 IV 974.]
Cycloleucine(52-52-8)Related Product Information
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