Icariin
- Product Name:Icariin
- CAS:489-32-7
- MF:C33H40O15
- MW:676.66
- EINECS:610-440-0
- Mol File:489-32-7.mol
-
Icariin Chemical Properties
- Melting point:223-225 ºC
- alpha D15 -87.09° (in pyridine)
- Boiling point:948.5±65.0 °C(Predicted)
- Density 1.55
- RTECS DJ2980500
- storage temp. room temp
- solubility DMSO: soluble50mg/mL, clear, colorless to dark yellow
- form Powder
- pka5.90±0.40(Predicted)
- color light yellow to yellow
- λmax350nm(MeOH)(lit.)
- Merck 14,3617
- InChIKeyTZJALUIVHRYQQB-XLRXWWTNSA-N
- Safety Statements 24/25
- WGK Germany 3
- HS Code 29389090
Icariin Usage And Synthesis
- Applications
Icariin inhibits the ROS-dependent JNK and p38 pathways.
- DescriptionIcariin is one of the major flavonoids of the herb Epimedium, which has long been used in Tranditional Chinese Medicine to treat bone fracture and prevent osteoporosis. Research has shown that icariin should be an effective component for the bone-strengthening activity of the herb Epimedium, and one of the possible mechanisms for this activity is to stimulate the proliferation and enhance the osteogenic differentiation of marrow stromal cells. Icariin is reported to prevent and treat sexual dysfunction related diseases and improve the use of vasoconstriction. Icariin is used to prepare angiotensin converting enzyme inhibitor medicines, which can be used to treat hypertension-complicated coronary diseases.
- References[1] K. M. Chen, B. F. Ge, H. P. Ma, X. Y. Liu, M. H. Bai, Y, Wang (2005) Icariin, a flavonoid from the herb Epimedium enhances the osteogenic differentiation of rat primary bone marrow stromal cells, 60, 939-942
[2] Patent CN 1199647C “Application of icariin in preparation of medicine for preventing and treating sexual dysfunction”
[3] Patent CN 104739851 A “New application of icariin, or icariin derivatives or icariin salt” - Chemical Properties
Light yellow to yellow solid
- Useshepatoprotective
- Apigenin D-(-)-Salicin Matrine NA Resveratrol KAEMPFEROL-7-O-GLUCOSIDE CHEMBRDG-BB 6564340 4-Acetyl-2-allylresorcinol 7-METHOXYFLAVONOL DESMETHYLXANTHOHUMOL Neoisoliquiritin 3-(2-METHOXY-5-METHYLPHENYL)-1-PROPENE ARTEMISININ ISOBAVACHALCONE Epmedin B 5,7-DIHYDROXY-3-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE Epimedin A Grape Seed Extract
IcariinSupplierMore
- Company Name:Wuhan Yijia Biotechnology Co., Ltd Gold
- Tel:19107255884
- Email:2013537414@qq.com
- Products Intro:Product Name:Icraiin
CAS:489-32-7
- Company Name:Shaanxi Pioneer Biotech Co.,Ltd Gold
- Tel:18629309720 29-84385017-8010
- Email:sales@pioneerbiotech.com
- Products Intro:Product Name:Icariin
CAS:489-32-7
Purity:10%~98% Package:1KG;25KG Remarks:1KG;25KG
- Company Name:Shanghai Hewu Biotechnology Co., LTD Gold
- Tel:17317861055 021-57886085
- Email:shhebio@126.com
- Products Intro:Product Name:Icariin;
CAS:489-32-7
Purity:HPLC＞98% Package:10mg 20mg 100mg 500mg 1g 10g Remarks:HPLC
- Company Name:J & K SCIENTIFIC LTD.
- Tel:400-666-7788 010-82848833-
- Email:jkinfo@jkchemical.com;market6@jkchemical.com
- Products Intro:Product Name:Icariin, 98%, from Epimedium brevicornu Maxim.
CAS:489-32-7
Purity:98% Package:100MG;25MG
- Company Name:INTATRADE GmbH
- Tel:+49 3493/605464
- Email:sales@intatrade.de
- Products Intro:Product Name:Icariin min 90% Synonyms 3-[(6-Deoxy-alpha-L-mannopyranosyl)oxy]-7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
CAS:489-32-7
Remarks:NN00324