White solid; walnut odor. Slightly soluble in alcohol.
7-Ethoxy-4-methylcoumarin may be used in the assay of 4-chlormethyl-7-ethoxycoumarin O-deethylase activity.
7-Ethoxy-4-methylcoumarin was an analyte in a study of the structural characterization and retention time simulation of allergenic fragrances.
ChEBI: 7-Ethoxy-4-methyl-2H-1-benzopyran-2-one is a member of coumarins.
7-Ethoxy-4-methylcoumarin (EtOMC), also known as ethyl 4-methylumbelliferyl ether, is a coumarin derivative. Its standard molar energy of combustion is ?5888.0 ± 3.2kJ·mol?1 and standard molar enthalpy of formation in the crystalline phase is ?545.4 ± 3.6kJ·mol?1.EtOMC can be prepared by reacting methyl acetoacetate with 3-ethoxyphenol in the presence of boron trifluoride dihydrate.The fluorescence quenching of EtOMC is more effective in the presence 4-hydroxy-TEMPO (4-hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl).
Prod.:
1) from Diketene plus Resorcinol with sulfuric
acid to produce 4-Methyl-7-hydroxy -
coumarin. Ethylation produces subject
material.
2) from Resorcinol plus Ethylacetoacetate,
followed by Ethylation.
