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Quinolinic acid

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Quinolinic acid Basic information
Quinolinic acid Chemical Properties
  • Melting point:188-190 °C (dec.)(lit.)
  • Boiling point:295.67°C (rough estimate)
  • Density 1.5216 (rough estimate)
  • refractive index 1.6280 (estimate)
  • storage temp. Store at RT
  • solubility 10g/l
  • pka2.43(at 25℃)
  • form Crystalline Powder
  • color White to light yellow-beige
  • Water Solubility 0.55 g/100 mL
  • Merck 14,8073
  • BRN 137110
  • InChIKeyGJAWHXHKYYXBSV-UHFFFAOYSA-N
  • CAS DataBase Reference89-00-9(CAS DataBase Reference)
  • EPA Substance Registry System2,3-Pyridinedicarboxylic acid (89-00-9)
Safety Information
MSDS
Quinolinic acid Usage And Synthesis
  • Chemical PropertiesWhite powder;Light yellow powder
  • UsesInhibits glucose synthesis
  • UsesAn inhibitor of glucose synthesis.
  • UsesA matabolite of tryptophan and a putative NMDA receptor agonist.
  • Synthesis Reference(s)Journal of the American Chemical Society, 71, p. 3020, 1949 DOI: 10.1021/ja01177a021
  • HazardA poison by skin contact. Moderately toxic by ingestion. A mild skin irritant.
  • Industrial usesThe use of quinolinic acid during flotation of hematite results in the adsorption of quinoline on hematite, allowing amine to selectively adsorb onto the hematite surface.
  • Biological ActivityEndogenous NMDA agonist and transmitter candidate. May distinguish between NMDA receptor subtypes.
  • Safety ProfileA poison by skin contact. Moderately toxic by ingestion. Experimental reproductive effects. A mdd skinn irritant. When heated to decomposition it emits toxic vapors of NOx.
Quinolinic acid Preparation Products And Raw materials
Quinolinic acid(89-00-9)Related Product Information
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