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Amoxicillin trihydrate

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Amoxicillin trihydrate Basic information
Amoxicillin trihydrate Chemical Properties
  • Melting point:>200°C (dec.)
  • alpha D20 +246° (c = 0.1)
  • refractive index 302 ° (C=0.1, H2O)
  • storage temp.  2-8°C
  • solubility Slightly soluble in water, very slightly soluble in ethanol (96 per cent), practically insoluble in fatty oils. It dissolves in dilute acids and dilute solutions of alkali hydroxides.
  • form neat
  • Water Solubility Soluble in water at 3.4mg/ml.
  • JECFA Number85
  • Merck 14,577
  • BRN 7507120
  • CAS DataBase Reference61336-70-7(CAS DataBase Reference)
  • EPA Substance Registry SystemAmoxicillin trihydrate (61336-70-7)
Safety Information
  • Hazard Codes Xn,Xi
  • Risk Statements 42/43
  • Safety Statements 36-36/37-22
  • WGK Germany 2
  • RTECS XH8300000
  • HS Code 29411000
  • ToxicityLD50 ipr-rat: 2870 mg/kg KSRNAM 7,3040,73
Amoxicillin trihydrate Usage And Synthesis
  • Chemical PropertiesWhite to Off-White Solid
  • UsesSemi-synthetic antibiotic related to Penicillin. Antibacterial.
  • DefinitionChEBI: A hydrate that is the trihydrate form of amoxicillin; a semisynthetic antibiotic, used either alone or in combination with potassium clavulanate (under the trade name Augmentin) for treatment of a variety of bacterial infections.
  • brand nameAmoxil (GlaxoSmithKline); Dispermox (Ranbaxy); Larotid (GlaxoSmithKline); Trimox (Apothecon) [Name previously used: Amoxycillin.].
  • Contact allergensAmoxicillin is both a topical and a systemic sensitizer. Topical sensitization occurs in health care workers. Systemic drug reactions are frequent, such as urticaria, maculo-papular rashes, baboon syndrome, acute generalized exanthematous pustulosis, or even toxic epidermal necrosis. Cross-reactivity is common with ampicillin, and can occur with other penicillins.
  • Safety ProfileModerately toxic. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx and NOx.
Amoxicillin trihydrate Preparation Products And Raw materials
Amoxicillin trihydrate(61336-70-7)Related Product Information
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