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QUINIDINE GLUCONATE

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QUINIDINE GLUCONATE Basic information
QUINIDINE GLUCONATE Chemical Properties
  • Melting point:175-176 C
  • form neat
Safety Information
  • Hazard Codes Xn,Xi
  • Risk Statements 20/21/22-36/37/38
  • Safety Statements 36-26
  • RIDADR 1544
  • WGK Germany 3
  • RTECS LZ5250000
  • HazardClass 6.1(b)
  • PackingGroup III
  • HS Code 2939200050
QUINIDINE GLUCONATE Usage And Synthesis
  • UsesCardiac depressant (anti-arrhythmic).
  • brand nameDuraquin (Warner Chilcott); Quinaglute (Berlex).
  • General DescriptionQuinidinium gluconate(Duraquin, Quinaglute) occurs as an odorless, very bitter,white powder. In contrast with the sulfate salt, it is freelysoluble in water. This is important because there are emergencieswhen the condition of the patient and the need for arapid response make the oral route of administration inappropriate.The high water solubility of the gluconate saltalong with a low irritant potential makes it valuable when aninjectable form is needed in these emergencies. Quinidinegluconate forms a stable aqueous solution. When used for injection, it usually contains 80 mg/mL, equivalent to 50 mgof quinidine or 60 mg of quinidine sulfate.
  • Veterinary Drugs and TreatmentsQuinidine is used in small animal or equine medicine for the treatment of ventricular arrhythmias (VPCs, ventricular tachycardia), refractory supraventricular tachycardias, and supraventricular arrhythmias associated with anomalous conduction in Wolff- Parkinson-White (WPW) syndrome. Chronic use of quinidine for controlling ventricular arrhythmias and supraventricular tachycardia in dogs has diminished over the years as other drugs appear to be more effective. It is still used in dogs and horses to convert atrial fibrillation to sinus rhythm. Oral therapy is generally not used in cats.
QUINIDINE GLUCONATE(7054-25-3)Related Product Information
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