The synthesis of 4-benzyloxybromobenzene was as follows: p-bromophenol, benzyl chloride, anhydrous potassium carbonate and potassium iodide were placed in a 250 ml three-necked flask and 170 ml of anhydrous ethanol was added. The reaction was heated and refluxed at 80 for 6h with stirring, and was detected by TLC .
TLC detection, the raw materials are basically reacted completely. The reaction was stopped and the reaction solution was poured into 1000ml distilled water.
distilled water, stirred thoroughly to remove the residual inorganic salts. Filtering, the class white solid, anhydrous ethanol recrystallization, 50g off-white powder, yield 88.5%.
