WHITE TO LIGHT YELLOW CRYSTALLINE POWDER
4-Imidazoleacetic acid hydrochloride was used in the synthesis of:
- imidazolyl-polyethylenimine modified nanoparticles
- pyridyl and imidazoyl functionalized carboproteins, potential metal ion chelators
A GABAc antagonistImidazole-4-acetic acid monohydrochloride is used in the preparation of imidazolyl-polyethylenimine modified nanoparticles. It is also used to prepare pyridyl and imidazoyl functionalized carboproteins and potential metal ion chelators. Further, it acts as an imidazole derivative with potential antituberculousis properties. In addition to this, it is used in the generation of acyl guanidine inhibitors of beta-secretas.
4-Imidazoleacetic acid hydrochloride is a competitive antagonist at GABAC receptors.
4-Imidazoleacetic acid hydrochloride is synthesized by reaction of imidazole-4(5)-acetic acid,amidine and dilute hydrochloric acid.
Imidazoleacetic acid (400 mg/kg; i.p.; single dose) hydrochloride increases the total free GABA pool size in mouse brain without a concomitant increase in the biosynthesis of GABA from glutamate[2].
Microbial Metabolite; Human Endogenous Metabolite
