ChemicalBook > Product Catalog > Pharmaceutical intermediates > Heterocyclic compound > Pyridine compound > Pyridine derivatives > 2-Hydroxy-5-pyridinecarboxylic acid
2-Hydroxy-5-pyridinecarboxylic acid
- Product Name:2-Hydroxy-5-pyridinecarboxylic acid
- CAS:5006-66-6
- MF:C6H5NO3
- MW:139.11
- EINECS:225-682-9
- Mol File:5006-66-6.mol
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2-Hydroxy-5-pyridinecarboxylic acid Chemical Properties
- Melting point:>300 °C(lit.)
- Boiling point:255.04°C (rough estimate)
- Density 1.4429 (rough estimate)
- refractive index 1.5423 (estimate)
- storage temp. Refrigerator
- pka3.80±0.50(Predicted)
- form Powder
- color Off-white to light brown
- BRN 472182
- InChIKeyBLHCMGRVFXRYRN-UHFFFAOYSA-N
- CAS DataBase Reference5006-66-6(CAS DataBase Reference)
- EPA Substance Registry System6-Hydroxynicotinic acid (5006-66-6)
- Hazard Codes Xi
- Risk Statements 36/37/38
- Safety Statements 26-36-24/25
- WGK Germany 3
- Hazard Note Irritant
- TSCA T
- HazardClass IRRITANT
- HS Code 29333990
- Language:EnglishProvider:2-Hydroxy-5-pyridinecarboxylic acid
- Language:EnglishProvider:ACROS
- Language:EnglishProvider:SigmaAldrich
- Language:EnglishProvider:ALFA
2-Hydroxy-5-pyridinecarboxylic acid Usage And Synthesis
- Chemical PropertiesOff-white powder
- Uses6-Hydroxynicotinic acid is used as building block in chemical synthesis.
- UsesNicotinic Acid derivative, found in fruit hypanthium.
- DefinitionChEBI: A monohydroxypyridine that is the 6-hydroxy derivative of nicotinic acid.
- Purification MethodsIt crystallises from water with m 303.4-303.7o(dec), or with m 325o(dec) from aqueous EtOH. The methyl ester crystallises from Me2CO with m 166o and pK2 0 9.92. [Albert J Chem Soc 1020 1960, Beilstein 22 III/IV 2147, 22/6 V 119.]
2-Hydroxy-5-pyridinecarboxylic acid Preparation Products And Raw materials
- 6-Chloronicotinic acid ETHYL 5-OXO-2-[2-(3-PYRIDINYLAMINO)VINYL]-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXYLATE METHYL 2-(METHOXYMETHYL)-7-METHYL-5-OXO-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXYLATE 1-BENZYL-6-OXO-1,6-DIHYDRO-3-PYRIDINECARBOXYLIC ACID 5-CHLORO-6-HYDROXY-3-PYRIDINECARBOXYLIC ACID 2,7-DIMETHYL-5-OXO-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXYLIC ACID ETHYL 2,7-DIMETHYL-5-OXO-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXYLATE METHYL 1-(2,6-DICHLOROBENZYL)-6-OXO-1,6-DIHYDRO-3-PYRIDINECARBOXYLATE 6-HYDROXY-5-(2-HYDROXYBENZOYL)-2-(TRIFLUOROMETHYL)NICOTINIC ACID 2,6-DIHYDROXY-4-METHYL-NICOTINIC ACID 2-METHYL-10-OXO-10H-9-OXA-1-AZA-ANTHRACENE-3-CARBOXYLIC ACID METHYL ESTER METHYL 2-(METHOXYMETHYL)-5-OXO-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXYLATE METHYL 2-ETHYL-7-METHYL-5-OXO-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXYLATE ETHYL 2-[2-(3,5-DICHLOROANILINO)VINYL]-5-OXO-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXYLATE 6-OXO-1-[3-(TRIFLUOROMETHYL)BENZYL]-1,6-DIHYDRO-3-PYRIDINECARBOXYLIC ACID 2,6-Dimethoxypyridine-3-carboxylic acid METHYL 2,7-DIMETHYL-5-OXO-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXYLATE 2-Hydroxy-5-pyridinecarboxylic acid
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