2-[(1-Naphthyloxy)methyl]oxirane

Glycidyl ethers are used as reactive diluents for epoxy resins. Alpha-naphtyl glycidyl ether is formed by adding epichlorhydrin and sodium hydroxide to alpha-naphtol. Contact dermatitis was reported in workers of a chemical plant.

2-[(1-Naphthyloxy)methyl]oxirane is Light Purple Oil

2-[(1-Naphthyloxy)methyl]oxirane is used in the preparation of Naftopidil (N213500) and propranolol (P831800).

Glycidyl ethers are used as reactive diluents for epoxy resins. Alpha-naphthyl glycidyl ether is formed by adding epichlorhydrin and NaOH to alpha-naphthol. Contact dermatitis was reported in workers of a chemical plant.

The α-naphthol and epichlorohydrin are heated and reacted, and after etherification, 1-chloro-3-(1-naphthyloxy)-2-propanol is generated, and then hydrogen chloride is removed under the action of sodium hydroxide to obtain 2-[ (1-Naphthyloxy)methyl]oxirane.