Basic information Safety Related Supplier
ChemicalBook >  Product Catalog >  Organic Chemistry >  Amides >  Acyclic polyamines and their derivatives >  Tetraacetylethylenediamine


Basic information Safety Related Supplier
Tetraacetylethylenediamine Basic information
Tetraacetylethylenediamine Chemical Properties
Safety Information
  • Safety Statements 22-24/25
  • WGK Germany 1
  • TSCA Yes
  • HS Code 29241900
Tetraacetylethylenediamine Usage And Synthesis
  • Chemical PropertiesTetraacetylethylenediamine is off-white to beige granular powder
  • UsesTetraacetylethylenediamine (TAED)  is a bleaching activator which is mainly used in detergents and additives for laundry washing and dishwashing. Typical concentrations of TAED range between 1.4% and 13% in these products. A small amount of the produced TAED is also used in bleaching of paper, textiles and for the generation of Peracetic acid.
    Peroxide bleach activator for household detergents, paper pulp.
  • PreparationTetraacetylethylenediamine (TAED) is produced in a two stage process from ethylenediamine (ED) and acetic anhydride (Ac2O). ED is first diacetylated to DAED. In the second step DAED is subsequently converted with Ac2O via TriAED into TAED (Clariant, 1999). TAED is crystallized out of the reaction mixture, filtered, washed and dried, and if necessary also granulated. The raw materials used occur almost quantitatively in the product. Byproducts are not formed.
    TAED was prepared by acetylation of diacetylethylenediamine (DAED) with acetic anhydride in a 5 L reactor coupled with a packed distillation column, 2.5 cm in inside diameter and 1 m in length. The reaction temperature was set at 135 °C and the reflux ratio at 6. The molar ratio of acetic anhydride to DAED was varied from 3 to 5. A TAED yield as high as 80% was obtained, higher by 15% than in the absence of distillation.
  • Health HazardTAED is of very low toxicity by all exposure routes examined. Up to 2 g/kg BW there is no acute toxicity. TAED is practically non-irritating to skin and eyes and there is no evidence of a sensitizing potential by skin contact. The only effect after repeated oral and dermal dosing was reversible centrilobular hypertrophy in the liver at high doses due to the induction of metabolizing enzymes. In a 90-day whole body inhalation study no adverse effects in the rat lung, respiratory tract or nasal mucosa were observed. Biokinetic data showed that TAED is rapidly absorbed from the rat intestine and largely metabolized via diacetylation to TriAED and DAED which are excreted in the urine.
Tetraacetylethylenediamine(10543-57-4)Related Product Information
  • Company Name:J & K SCIENTIFIC LTD.
  • Tel:400-666-7788 010-82848833-
  • Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
  • Tel:400-660-8290 21-61259100-
  • Company Name:future industrial shanghai co., ltd
  • Tel:400-0066-400
  • Company Name:Alfa Aesar
  • Tel:400-610-6006
  • Company Name:TCI (Shanghai) Development Co., Ltd.
  • Tel:021-67121386 / 800-988-0390