2,2'-DIPICOLYLAMINE

In a 100mL three-necked flask, 2-formylpyridine (10mmol) was added, and under stirring conditions, 20mL of methanol solution of 2-aminomethylpyridine (10mmol) was added dropwise to 2-formylpyridine, and stirred at room temperature for 10h after the dropwise addition was completed. NaBH4 (20mmol) was added to the reaction system in several portions and slowly, and the reaction solution turned from brown to light yellow, and stirred at room temperature overnight. Light yellow, stirring at room temperature overnight, evaporate the solvent under reduced pressure, then add 20mL distilled water, under stirring with 32% dilute hydrochloric acid to pH neutral, extracted with dichloromethane (3 30mL), collect the lower layer of the yellow solution with anhydrous MgSO4 drying, distillation under reduced pressure to obtain a yellow liquid, the yield of 95%.