yellow crystalline powder
Thioacetanilide (N-Phenylthioacetamide) is a thioderivative of acetanilide that exhibits Z/E isomer preference and solvent dependence[1].
Metabolism and acute toxicity of thioacetanilide has been studied in rat. Thioacetanilide undergoes nucleophilic addition reaction with superoxide ion in dimethyl sulfoxide.
[1] Song S, et al. Contribution of Solvents to Geometrical Preference in the Z/E Equilibrium of N-Phenylthioacetamide. J Org Chem. 2022 Feb 4;87(3):1641-1660. DOI:
10.1021/acs.joc.1c00801
