Flusulfamide is a fungicide used as a soil treatment to control club root and other root diseases. It has a low aqueous solubility and a low volatility. There are significant gaps in data relatd to environmental fate and human toxicity but oral mammalian toxicity is moderate. Toxicity to biodiversity tends to be moderate but gaps in data exist,
Flusulfamide is a fungicide used in pesticide formulations in the treatment of crops.
ChEBI: A sulfonamide resulting from the formal condensation 4-chloro-3-(trifluoromethyl)benzenesulfonic acid with 2-chloro-4-nitroaniline. A fungicide, it is used to control Plasmodiophora brassicae in brassicas and Polymyxa betae in sug
rbeet.
Mode of action is unclear but thought to be due to the compound's effects on the spore cell wall or on the protein folding processes involved in spore development and so inhibits spore germination
The synthesis of flusulfamide involves the following steps: 1. Synthesis of a sulfonamide precursor from o-chlorotoluene or p-nitroaniline as starting materials. 2. Reaction of this intermediate with a heterocyclic compound (typically a substituted pyridine or analogous ring system) under controlled conditions to form the active sulfonamide bond. 3. Finally, the target product is obtained by condensation and substitution reactions. The reaction formula is as follows:
