A new alkaloid of the protoberberine group, this base occurs in Stephania giabra.
The structure has been assigned on the basis of chemical and spectroscopic
evidence.
A tetrahydroprotoberberine agonist at dopamine D1 and antagonist at D2 receptors. It is used for preventing or treating neural diseases. The neural diseases comprise parkinsonism, schizophrenia and dyskinesia which is produced by L-DOPA or medicine to treat schizophrenia. Antipsychotics.
A tetrahydroprotoberberine agonist at dopamine D1 and antagonist at D2 receptors.
dyskinesia which is produced by L-DOPA or medicine to treat schizophrenia. Antipsychotics.
Dopamine Receptor | 5-HT Receptor
Cava et ai., f. Org. Chern., 33,2785 (1968)
