Description
A new alkaloid of the protoberberine group, this base occurs in Stephania giabra.
The structure has been assigned on the basis of chemical and spectroscopic
evidence.
Chemical Properties
Pink Solid
Uses
A tetrahydroprotoberberine agonist at dopamine D1 and antagonist at D2 receptors. It is used for preventing or treating neural diseases. The neural diseases comprise parkinsonism, schizophrenia and dyskinesia which is produced by L-DOPA or medicine to treat schizophrenia. Antipsychotics.
Uses
A tetrahydroprotoberberine agonist at dopamine D1 and antagonist at D2 receptors.
dyskinesia which is produced by L-DOPA or medicine to treat schizophrenia. Antipsychotics.
target
Dopamine Receptor | 5-HT Receptor
References
Cava et ai., f. Org. Chern., 33,2785 (1968)
