Basic information Description References Safety Related Supplier

Isoxazole

Basic information Description References Safety Related Supplier
Isoxazole Basic information
Isoxazole Chemical Properties
  • Melting point:-67.1°C
  • Boiling point:93-95 °C(lit.)
  • Density 1.078 g/mL at 25 °C(lit.)
  • vapor density 2.4 (vs air)
  • refractive index n20/D 1.427(lit.)
  • Flash point:48 °F
  • storage temp. Store at RT.
  • solubility 167g/l
  • pka-2.0(at 25℃)
  • BRN 103773
  • InChIKeyCTAPFRYPJLPFDF-UHFFFAOYSA-N
  • CAS DataBase Reference288-14-2(CAS DataBase Reference)
  • NIST Chemistry ReferenceIsoxazole(288-14-2)
  • EPA Substance Registry SystemIsoxazole (288-14-2)
Safety Information
  • Hazard Codes F,Xi
  • Risk Statements 11
  • Safety Statements 16-23/33-33-29-7/9
  • RIDADR UN 1993 3/PG 2
  • WGK Germany 3
  • 10
  • Hazard Note Highly Flammable
  • TSCA Yes
  • HazardClass 3
  • PackingGroup II
  • HS Code 29349990
MSDS
Isoxazole Usage And Synthesis
  • DescriptionAs an important class of heterocycles, isoxazole is a five membered heterocyclic compound with various pharmacological actions, which is found in some natural products, such as ibotenic acid. It is used in the formation of the basis for a number of drugs, such as the COX-2 inhibitor valdecoxib and anti-inflammatory drugs. Isoxazoles are largely applied in the area of pharmaceuticals and therapeutics, including insecticidal, antibacterial, antibiotic, antitumour, antifungal, antituberculosis, anticancer and ulcerogenic. Besides, it has a great effect on reducing blood glucose, eliminating pain, resisting inflammation, killing harmful bacteria, controlling and reducing the risk of HIV.
    The isoxazole ring is an essential pharmacophore in modern drug discovery. Some beta-lactamase-resistant antibiotics contain an isoxazole group, including cloxacillin, dicloxacillin, flucloxacillin, and the isoxazole group is also found in some steroid drug such as danazol.
  • Referenceshttps://en.wikipedia.org/wiki/Isoxazole
    http://www.ijpcbs.com/files/volume3-2-2013/15.pdf
  • Chemical PropertiesColorless liquid
  • UsesNatural insecticide.
  • DefinitionChEBI: A monocyclic heteroarene with a structure consisting of a 5-membered ring containing three carbon atoms and an oxygen and nitrogen atom adjacent to each other. It is the parent of the class of isoxazoles.
  • HazardNarcotic and psychomimetic effects.
Isoxazole Preparation Products And Raw materials
Isoxazole(288-14-2)Related Product Information
IsoxazoleSupplierMore
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    CAS:288-14-2
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    CAS:288-14-2
    Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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    CAS:288-14-2
    Package:5g Remarks:L01607
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