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17-DMAG

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17-DMAG Basic information
  • Product Name:17-DMAG
  • CAS:467214-21-7
  • MF:C32H48N4O8
  • MW:616.75
  • EINECS:
  • Mol File:Mol File
17-DMAG Chemical Properties
  • storage temp. Store at -20
  • form Purple solid
  • InChIKeyKUFRQPKVAWMTJO-LMZWQJSESA-N
17-DMAG Usage And Synthesis
  • UsesTreatment of solid and hematological tumors.
  • Enzyme inhibitorThis potent Hsp90 inhibitor (FWHCl-Salt = 653.21 g/mol; CAS 467214-21-7), also named 17-DMAG and 17-demethoxy-17-[[2-(dimethylamino) ethyl]amino]geldanamycin, targets Heat Shock Protein-90 (IC50 = 62 nM in a cell-free assay). (See also Ansamycin; Deguelin; Derrubone; Ganetespib; Geldanamycin; Herbimycin; Macbecin; Radicicol; Tanespimycin; and the nonansamycin Hsp90 inhibitor KW-2478)
17-DMAG(467214-21-7)Related Product Information
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