Poly(A) has been used for droplet digital PCR (ddPCR) assay.
POLYADENYLIC ACID (5') POTASSIUM SALT is used to evaluate binding on cationic liposomes doped with non-ionic nucleolipids. Poly-A is used in small molecule mRNA targeted drug development to evaluate the binding of potential therapeutic agents such as the Isoquinoline group of alkaloids.
Poly(A) is used as a carrier for quantitative precipitation of DNA and RNA.
Polyadenylic acid (Poly(A)) tails present at 3′ end are produced in the cell nucleus. It contains ~250 nucleotides in mammalian cells.?Poly(A) regulates mRNA decay and the initiation of translation. Cytoplasmic poly(A) extension modulates translation.