p-Anisohydrazide

• N′-[(E)-5-bromo-2-hydroxy-3-methoxybenzylidene]-4-methoxybenzohydrazide monohydrate
• 2,5-bis(4-methoxyphenyl)-1,3,4-oxadiazole
• hydrazone ligands, which readily forms ruthenium(II) hydrazone complexes via reaction with [RuHCl(CO)(PPh₃)₃]

121-98-2

3290-99-1

4-Methoxybenzoic acid hydrazide was synthesized according to literature [22]. A mixture of methyl 4-methoxybenzoate (1.66 g, 10 mmol) with 80% hydrazine hydrate (3.6 mL, 60 mmol) in anhydrous ethanol (20 mL) was heated and refluxed for 6 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure to give a white precipitate. The crude product was recrystallized from anhydrous ethanol to give 4-methoxybenzohydrazide as colorless needle-like crystals. Yield 96%, melting point 138-139°C (literature values in accordance).