Basic information Description Application Description References Safety Related Supplier
ChemicalBook >  Product Catalog >  Chemical Reagents >  Organic reagents >  Aromatic acids >  Anisic acid

Anisic acid

P-anisic acid, known also as 4-methoxybenzoic acid or draconic acid, is an organic acid with sweet flavor. It is one of the isomers (m-anisic acid, and o-anisic acid) of anisic acid. The term anisic acid is often used to describe p-anisic acid. P-anisic acid is produced through the oxidation of p-cresyl-methyl ether.

Basic information Description Application Description References Safety Related Supplier
Anisic acid Basic information
Anisic acid Chemical Properties
  • Melting point:182-185 °C(lit.)
  • Boiling point:275 °C
  • Density 1.385
  • FEMA 3945 | 4-METHOXYBENZOIC ACID
  • refractive index 1.571-1.576
  • Flash point:185 °C
  • storage temp. Store below +30°C.
  • solubility H2O: soluble2500 parts
  • pka4.50(at 25℃)
  • form Powder
  • color White to slightly gray-beige
  • PH3-4 (0.3g/l, H2O, 20℃)
  • Water Solubility Soluble in water at 20°C 0.3g/L. Soluble in alcohol, ethyl acetate and ether.
  • JECFA Number883
  • Merck 14,666
  • BRN 508910
  • Stability:Stable. Incompatible with strong oxidizing agents.
  • InChIKeyZEYHEAKUIGZSGI-UHFFFAOYSA-N
  • CAS DataBase Reference100-09-4(CAS DataBase Reference)
  • NIST Chemistry ReferenceBenzoic acid, 4-methoxy-(100-09-4)
  • EPA Substance Registry SystemBenzoic acid, 4-methoxy- (100-09-4)
Safety Information
  • Hazard Codes Xi,Xn
  • Risk Statements 36/37/38-22
  • Safety Statements 26-36-24/25
  • WGK Germany 1
  • RTECS BZ4395000
  • Autoignition Temperature185 °C
  • Hazard Note Irritant
  • TSCA Yes
  • HS Code 29189090
  • ToxicityLD50 orally in Rabbit: > 5000 mg/kg
MSDS
Anisic acid Usage And Synthesis
  • DescriptionAnisic acid or methoxybenzoic acid is an organic compound which is a carboxylic acid. P-Anisic acid, known also as 4-methoxybenzoic acid or Draconic acid, which is a methoxybenzoic acid substituted with a methoxy group at position C-4, and P-Anisic acid is an organic acid with sweet flavor. It is one of the isomers (m-anisic acid, and o-anisic acid) of anisic acid. The term anisic acid is often used to describe p-anisic acid and P-anisic acid is produced through the oxidation of p-cresyl-methyl ether. P-Anisic acid is a carboxylic acid found naturally in anise, a flowering plant in the family Apiaceae. P-Anisic acid exists as a white crystalline solid which is insoluble in water, highly soluble in alcohols, and soluble in ether and ethyl acetate.
  • ApplicationP-Anisic acid is used mostly as photographic chemicals and dye intermediate. It is also used as fragrance and flavoring agent for pharmaceuticals, drug, antimicrobial (against bacterias, mold and yeast), repellent, ovicide, antirheumatic agent, synthetic flavoring agent in foods, lab reagent, fragrance ingredient, and odor masking agent for products, furthermore, it is also used for the preparation of p-aniosylchloride.
    P-Anisic acid has antiseptic properties and is typically used as a preservative in cosmetics and skin care products. Because P-Anisic acid is derived from anise, a flowering plant native, it is safe ingredients in cosmetics to replace potentially toxic preservatives like parabens in some natural or organic skin care products.
  • DescriptionP-anisic acid, known also as 4-methoxybenzoic acid or draconic acid, is an organic acid with sweet flavor. It is one of the isomers (m-anisic acid, and o-anisic acid) of anisic acid. The term anisic acid is often used to describe p-anisic acid. P-anisic acid is produced through the oxidation of p-cresyl-methyl ether.
    P-anisic acid is used mostly as photographic chemicals and dye intermediate. It is also used as fragrance and flavoring agent for pharmaceuticals, drug, antimicrobial (against bacterias, mold and yeast), repellent, ovicide, antirheumatic agent, synthetic flavoring agent in foods, lab reagent, fragrance ingredient, and odor masking agent for products. It is also used for the preparation of p-aniosylchloride. Furthermore, it is marketed as preservative-free for surfactant based formulations, such as shampoos, shower gels, and bubble baths.
  • References[1] Michael Ash (2004) Handbook of Preservatives
    [2] Asim Kumar Mukhopadhyay (2004) Industrial Chemical Cresols and Downstream Derivatives
    [3] https://en.wikipedia.org/wiki/P-Anisic_acid
  • Chemical Propertieswhite powder
  • Chemical Properties4-Methoxybenzoic acid is practically odorless.
  • UsesIntermediates of Liquid Crystals
  • DefinitionChEBI: A methoxybenzoic acid substituted with a methoxy group at position C-4.
  • Safety ProfilePoison by subcutaneous route.When heated to decomposition it emits acrid smoke andirritating vapors.
  • Purification MethodsCrystallise p-anisic acid from EtOH, water, EtOH/water or toluene. The S-benzylisothiuronium salt has m 189o (from EtOH). [Beilstein 10 II 91, 10 III 280, 10 IV 346.]
Anisic acid Preparation Products And Raw materials
Anisic acid(100-09-4)Related Product Information
Anisic acidSupplierMore
  • Company Name:Changzhou Xianlin Pharmaceutical Co., Ltd. Gold
  • Tel:13205218370
  • Email:xlswyy@126.com
  • Products Intro:Product Name:p-Anisic acid
    CAS:100-09-4
    Purity:99% Package:1 kg/
  •  
  • Company Name:BeiLi Technology (Chongqing) Co., Ltd. Gold
  • Tel:13862420197 512-58635988
  • Email:sales@beili.com
  • Products Intro:Product Name:4-methoxybenzoic acid
    CAS:100-09-4
    Purity:99.00% Package:25KG/0.10;
  •  
  • Company Name:Hebei Huanhao Biotechnology Co. Ltd. Gold
  • Tel:18034552304 0311-83975816-
  • Email:joydxk@hbhuanhao.com
  • Products Intro:Product Name:4-Methoxybenzoic acid
    CAS:100-09-4
    Purity:99% Package:25 kg / bag
  •  
  • Company Name:Zheda Panaco (Shandong) Chemical Enginering Co., Ltd. Gold
  • Tel:13805730994 0530-8865559-000
  • Email:panaco@zhedachem.com
  • Products Intro:Product Name:P-Methoxybenzoic acid
    CAS:100-09-4
    Purity:99% Package:25-Kg Fiber drum
  •  
  • Company Name:Hubei Ovicks Trading Co. Ltd. Gold
  • Tel:15377599627
  • Email:admin@aoksbio.com
  • Products Intro:Product Name:Anisic acid
    CAS:100-09-4
    Purity:99% Package:1KG/ Remarks:factory supply
  •  
Related articles