METHYL 2-HYDROXYOCTADECANOATE

2-hydroxy Stearic acid is a hydroxylated fatty acid methyl ester that broadens phase transition in dimyristoylphosphatidylcholine (DMPC) lipid membranes. It has been used in the synthesis of lipid-nucleotide conjugate anti-HIV agents to increase phosphodiester bond cleavage and the amount of liberated intracellular nucleotides. [Matreya, LLC. Catalog No. 1708]

Methyl (+/-)-2-hydroxystearateis a hydroxylated fatty acid methyl ester that broadens phase transitions in dimyristoylphosphatidylcholine (DMPC) lipid membranes. It has been used in the synthesis of lipid-nucleotide conjugated anti-HIV agents to increase the cleavage of phosphodiester bonds and the number of released intracellular nucleotides.

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[2] KISHORE LINGAM GANGADHARA . Hydroxy fatty acids for the delivery of dideoxynucleosides as anti-HIV agents[J]. Bioorganic & Medicinal Chemistry Letters, 2014, 24 3: Pages 817-820. DOI: 10.1016/j.bmcl.2013.12.093