Basic information Safety Related Supplier
ChemicalBook >  Product Catalog >  Biochemical Engineering >  Inhibitors >  Metabolism >  PDE inhibitors >  ROLIPRAM

ROLIPRAM

Basic information Safety Related Supplier
ROLIPRAM Basic information
ROLIPRAM Chemical Properties
  • Melting point:127-133 °C
  • Boiling point:418.29°C (rough estimate)
  • Density 1.0677 (rough estimate)
  • refractive index 1.5500 (estimate)
  • storage temp.  0-6°C
  • solubility H2O: 0.2 mg/mL
  • form solid
  • pka16.02±0.40(Predicted)
  • color white to off-white
  • Merck 14,8251
Safety Information
  • Hazard Codes Xi
  • Risk Statements 36/37/38-11
  • Safety Statements 26-36
  • RIDADR 3249
  • WGK Germany 3
  • RTECS UY5749237
  • HazardClass 6.1(b)
  • PackingGroup III
  • HS Code 29337900
  • ToxicityLD50 oral in mouse: > 300mg/kg
MSDS
ROLIPRAM Usage And Synthesis
  • Chemical PropertiesYellowish solid
  • Usesantipsychotic
  • UsesA selective, cell permeable inhibitor of cAMP-specific phosphodiesterase (PDE4).
  • UsesPharmacological tool for characterization of phosphodiesterase isoenzymes.
  • Biological ActivitySelective inhibitor of cAMP phosphodiesterase (PDE4) (IC 50 = 2.0 μ M). Discriminates between two conformational states of PDE4 isoenzymes. See separate isomers ((R)-(-)-Rolipram and (S)-(+)-Rolipram).
ROLIPRAM(61413-54-5)Related Product Information
ROLIPRAMSupplierMore
  • Company Name:J & K SCIENTIFIC LTD.
  • Tel:400-666-7788 010-82848833-
  • Email:jkinfo@jkchemical.com;market6@jkchemical.com
  •  
  • Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
  • Tel:18930552037 821-50328103-801
  • Email:3bsc@sina.com
  •  
  • Company Name:TCI (Shanghai) Development Co., Ltd.
  • Tel:021-67121386 / 800-988-0390
  • Email:Sales-CN@TCIchemicals.com
  •  
  • Company Name:Ascent Scientific
  • Tel:4401179829988
  • Email:customerservice@ascentscientific.co.uk
  •  
  • Company Name:Chemfun Medical Technology(Shanghai) Co., Ltd.
  • Tel:021-67220633 & 021-37212706
  • Email:chemfun@chemfun.net
  •