ChemicalBook > Product Catalog > Biochemical Engineering > Inhibitors > Metabolism > PDE inhibitors > ROLIPRAM
ROLIPRAM
- Product Name:ROLIPRAM
- CAS:61413-54-5
- MF:C16H21NO3
- MW:275.34
- EINECS:262-771-1
- Mol File:61413-54-5.mol
-
ROLIPRAM Chemical Properties
- Melting point:127-133 °C
- Boiling point:418.29°C (rough estimate)
- Density 1.0677 (rough estimate)
- refractive index 1.5500 (estimate)
- storage temp. 0-6°C
- solubility H2O: 0.2 mg/mL
- form solid
- pka16.02±0.40(Predicted)
- color white to off-white
- Merck 14,8251
- Hazard Codes Xi
- Risk Statements 36/37/38-11
- Safety Statements 26-36
- RIDADR 3249
- WGK Germany 3
- RTECS UY5749237
- HazardClass 6.1(b)
- PackingGroup III
- HS Code 29337900
- ToxicityLD50 oral in mouse: > 300mg/kg
- Language:EnglishProvider:SigmaAldrich
- Language:EnglishProvider:ACROS
ROLIPRAM Usage And Synthesis
- Chemical PropertiesYellowish solid
- Usesantipsychotic
- UsesA selective, cell permeable inhibitor of cAMP-specific phosphodiesterase (PDE4).
- UsesPharmacological tool for characterization of phosphodiesterase isoenzymes.
- Biological ActivitySelective inhibitor of cAMP phosphodiesterase (PDE4) (IC 50 = 2.0 μ M). Discriminates between two conformational states of PDE4 isoenzymes. See separate isomers ((R)-(-)-Rolipram and (S)-(+)-Rolipram).
- Donepezil PP242 Milrinone WORTMANNIN Vinpocetine Cilostazol Forskolin 2-Pyrrolidinone S-Desmethyl-Rolipram (+)-Desmethyl-Rolipram,R-Desmethyl-Rolipram (R,S)-Desmethyl-Rolipram (R)-(-)-ROLIPRAM, >98% ROLIPRAM--N/H S- (+)-Rolipram ROLIPRAM [6-3H] (R)-(-)-ROLIPRAM,(S)-(+)-ROLIPRAM,Rolipram (R)-(-)- ROLIPRAM [METHYL-3H]ROLIPRAM
ROLIPRAMSupplierMore
- Company Name:J & K SCIENTIFIC LTD.
- Tel:400-666-7788 010-82848833-
- Email:jkinfo@jkchemical.com;market6@jkchemical.com
- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:18930552037 821-50328103-801
- Email:3bsc@sina.com
- Company Name:TCI (Shanghai) Development Co., Ltd.
- Tel:021-67121386 / 800-988-0390
- Email:Sales-CN@TCIchemicals.com
- Company Name:Ascent Scientific
- Tel:4401179829988
- Email:customerservice@ascentscientific.co.uk
- Company Name:Chemfun Medical Technology(Shanghai) Co., Ltd.
- Tel:021-67220633 & 021-37212706
- Email:chemfun@chemfun.net