The commercial production of dikegulac sodium typically begins with 2-keto-L-gulonic acid. This precursor is reacted with 2,2-dimethoxypropane under elevated temperatures in the presence of a strong acid catalyst, such as sulphuric acid, to form a protected intermediate via acetal formation. This intermediate contains the diacetonide structure characteristic of dikegulac. The reaction mixture is then treated with a base, often sodium hydroxide, to hydrolyse residual esters and neutralise the acid, yielding dikegulac sodium.
Systemic, decreases RNA synthesis, rapidly inhibits amino-acid uptake by cells, absorbed by leaves and roots.
