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Clarithromycin Structure

Clarithromycin

Chemical Properties

Melting point 217-220°C
Boiling point 86℃
alpha  D24 -90.4° (c = 1 in CHCl3)
Density  1.1334 (rough estimate)
refractive index  -92 ° (C=1, CHCl3)
Flash point >110°(230°F)
storage temp.  -20°C
solubility  Soluble in DMSO
pka pKa 8.99(H2O t=25.0 I=0.167) (Uncertain)
form  powder
color  colorless to faint yellow
Water Solubility  99.48mg/L(20 ºC)
Merck  14,2339
BCS Class 4
Stability Store in Freezer
InChIKey AGOYDEPGAOXOCK-KCBOHYOISA-N
EPA Substance Registry System Erythromycin, 6-O-methyl- (81103-11-9)

Safety Information

Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  26-36-60
WGK Germany  3
RTECS  KF4997000
HS Code  29419000
Hazardous Substances Data 81103-11-9(Hazardous Substances Data)
Toxicity LD50 in male, female mice, male, female rats (mg/kg): 2740, 2700, 3470, 2700 orally, 1030, 850, 669, 753 i.p., >5000 all s.c. (Abe)

MSDS

Usage And Synthesis

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