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ACRIFLAVINE

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ACRIFLAVINE Basic information
ACRIFLAVINE Chemical Properties
  • Melting point:179-181 °C
  • Boiling point:612.69°C (rough estimate)
  • Density 1.0933 (rough estimate)
  • refractive index 1.6000 (estimate)
  • solubility H2O: soluble0.33g/mL (lit.)(lit.)
  • form Powder
  • color Deep orange to brownish-red
  • Merck 14,123
  • CAS DataBase Reference8048-52-0(CAS DataBase Reference)
  • EPA Substance Registry SystemXanthacridinum (8048-52-0)
Safety Information
MSDS
ACRIFLAVINE Usage And Synthesis
  • Chemical PropertiesAcriflavine hydrochloride is deep orange to brownish-red powder
  • UsesAcriflavine is used in applications for dual fluorescence analysis of cellular DNA and protein simultaneously.
  • UsesFluorescent label for high molecular weight RNA
  • Safety ProfilePoison by subcutaneous route. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. A topical antiseptic used in the treatment of gonorrhea. When heated to decomposition it emits very toxic fumes of NOx and Cl-. See also 3,6-DIAMINO-10 METHYLACRIDINIUM CHLORIDE.
  • Purification MethodsTreat acriflavin twice with freshly precipitated AgOH to remove proflavine, then recrystallise it from absolute methanol [Wen & Hsu J Phys Chem 66 1353 1962]. [Beilstein 22 III/IV 218.]
ACRIFLAVINE(8048-52-0)Related Product Information
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