Acriflavine hydrochloride is deep orange to brownish-red powder
Acriflavine is used in applications for dual fluorescence analysis of cellular DNA and protein simultaneously.
Fluorescent label for high molecular weight RNA
Poison by
subcutaneous route. Questionable
carcinogen with experimental tumorigenic
data. Human mutation data reported. A
topical antiseptic used in the treatment of
gonorrhea. When heated to decomposition
it emits very toxic fumes of NOx and Cl-.
See also 3,6-DIAMINO-10
METHYLACRIDINIUM CHLORIDE.
Treat acriflavin twice with freshly precipitated AgOH to remove proflavine, then recrystallise it from absolute methanol [Wen & Hsu J Phys Chem 66 1353 1962]. [Beilstein 22 III/IV 218.]
