苦木素 性质
| 熔点 | 222° |
|---|---|
| 比旋光度 | D20 +34.5° (c = 5.09 in CHCl3) |
| 沸点 | 586.3±50.0 °C(Predicted) |
| 密度 | 1.23±0.1 g/cm3(Predicted) |
| 储存条件 | -20°C Freezer, Under inert atmosphere |
| 溶解度 | 可溶于氯仿（少许）、甲醇（少许） |
| 形态 | 固体 |
| 颜色 | 白色至类白色 |
| 旋光性 (optical activity) | +34.520 (c 5.09, CHCl3) |
| LogP | 2.220 (est) |
| EPA化学物质信息 | Picrasa-2,12-diene-1,11,16-trione, 2,12-dimethoxy- (76-78-8) |
苦木素 用途与合成方法
Quassin (Nigakilactone D) 是一种从 Quassia amara 的茎皮提取物中提取的生物活性三萜。Quassin 抑制 P. falciparum，IC50 为 0.15 μM。Quassin 具有可逆的抗生育能力，抗雌激素和抗疟原虫活性。
IC50: 0.15 μM ( P. falciparum )
Quassin (Compound 1; 5-25 ng/mL) inhibits both the basal and luteinizing hormone-stimulated testosterone secretion of rat Leydig cells in a dose-dependent fashion.
Quassin (0.1-2.0 mg/kg; oral administration; daily; for 60 days; females albino rats) treatment shows a significant decrease in the weight of the ovary and uterus. And also shows a significant decrease in serum estrogen levels in quassin treated rats. The Quassin treated rats has a significantly decreased mean litter number and weight. Quassin does not adversely affect the weight of the kidney, heart, liver and the body of the rats.
| Animal Model: | 35 females albino rats (150-170 g) |
| Dosage: | 0.1 mg/kg, 1.0 mg/kg and 2.0 mg/kg |
| Administration: | Oral administration; daily; for 60 days |
| Result: | There was a significant decrease in the weight of the ovary and uterus in all the groups relative to the control. There was also a significant decrease in serum estrogen levels in quassin treated rats. |
用途
Quassin is a naturally occurring extract from quassia trees and is used in traditional chinese medicine for it鈥檚 antiulcerogenic properties. Quassin have also been used as an additive in soft drinks. 苦木素 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024-11-08 | HY-N1581 | 苦木素 | 76-78-8 | 1mg | 900 |
| 2024-11-08 | HY-N1581 | 苦木素 | 76-78-8 | 5mg | 3600 |
苦木素供应商 更多
成都普思生物科技股份有限公司
黄金产品
联系电话： 18080489829
产品介绍：
中文名称：苦木素
英文名称：Quassin
CAS：76-78-8
纯度：95.0%（HPLC）
包装信息：5mg
备注：现货供应，当天发货
北京百灵威科技有限公司
联系电话：010-82848833 400-666-7788
产品介绍：
英文名称：Quassin
CAS：76-78-8
包装信息：2.5Mg,25Mg
备注：化学试剂、精细化学品、医药中间体、材料中间体
云南西力生物技术股份有限公司
联系电话：0871-65217109 13211707573;
产品介绍：
中文名称：苦木素
英文名称：Quassin
CAS：76-78-8
纯度：96.0%
包装信息：5mg
备注：BBP01338
上海融禾医药科技发展有限公司
联系电话：400-186-5138 13341702378
产品介绍：
中文名称：苦木素
英文名称：Quassin
CAS：76-78-8
纯度：HPLC>=98%
包装信息：10mg;20mg;100mg;1g
备注：更多包装规格请微信或QQ详询，可根据包装需求分装，量大从优，欢迎订购！13341702378（微信同号）
