- Product Name:Alginic acid
- Synonyms: Mixed polymer of mannuronic and guluronic acid Nopgine ALGINIC ACID FREE ACID FROM MACROCYSTIS PYRIFERA (K ALGINIC ACID, FROM BROWN ALGAE AlginicAcid,SodiumSalt,~99% alginic acid from macrocystis pyrifera (kelp) ALGINICACID,FCC ALGINICACID,NF
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- Mol File:Mol File
Alginic acid Chemical Properties
- Melting point:300 °C
- solubility H2O: insoluble, but swells
- form Powder
- color White to pale yellow to beige
- Water Solubility Insoluble in water.
- Sensitive Hygroscopic
- Merck 14,242
- EPA Substance Registry SystemAlginic acid(9005-32-7)
Alginic acid Usage And Synthesis
- Chemical Propertieswhite to pale yellow-beige powder
- Chemical PropertiesAlginic acid is a tasteless, practically odorless, white to yellowishwhite, fibrous powder.
- UsesGum derived from alginic acid which is obtained from brown seaweed genera, such as Macrocystis pyrifera. The derivatives are sodium, ammonium, and potassium ates of which the sodium salt is most common. They are used to provide thickening, gelling, and binding. A derivative designed for improved acid and calcium stability is propylene glycol ate. The s are soluble in cold water and form nonthermoreversible gels in reaction with calcium ions and under acidic conditions. Algin is used in ice cream, icings, puddings, dessert gels, and fabricated fruit.
- Usescorrosive moisture sensitive
- Usesalgin (alginic acid) is used in cosmetic formulations as a thickener, stabilizer, and gelling agent. It is obtained from different varieties of brown seaweed.
- UsesAlginic Acid is the acidic, insoluble form of algin that is a white to yellowish fibrous powder obtained from brown seaweed genera, such as macrocystis pyrifera. the derivatives are soluble and include sodium, potassium, and ammonium alginate and propylene glycol alginate. it is used as a tablet disintegrant and as an antacid ingredient.
- DefinitionA polysaccharide composed of β,d-mannuronic acid residues linked so that the carboxyl group of each unit is free, while the aldehyde group is shielded by a glycosidic linkage. It is a linear polymer of the mannuronic acid in the pyranose ring form.
- Production MethodsAlginic acid is a hydrophilic colloid carbohydrate that occurs naturally in the cell walls and intercellular spaces of various species of brown seaweed (Phaeophyceae). The seaweed occurs widely throughout the world and is harvested, crushed, and treated with dilute alkali to extract the alginic acid.
- DefinitionA yellow-white organic solid that is found in brown algae. It is a complex polysaccharide and produces, in even very dilute solutions, a viscous liquid. Alginic acid has various uses, especially in the food industry as a stabilizer and texture agent.
- Pharmaceutical ApplicationsAlginic acid is used in a variety of oral and topical pharmaceutical
formulations. In tablet and capsule formulations, alginic acid is used
as both a binder and disintegrating agent at concentrations of 1–5%
w/w. Alginic acid is widely used as a thickening and suspending
agent in a variety of pastes, creams, and gels; and as a stabilizing
agent for oil-in-water emulsions.
Alginic acid has been used to improve the stability of levosimendan.
Therapeutically, alginic acid has been used as an antacid.In combination with an H2-receptor antagonist, it has also been utilized for the management of gastroesophageal reflux.
- Safety ProfileModerately toxic by intraperitoneal route. When heated to decomposition it emits acrid smoke and irritating fumes
- SafetyAlginic acid is widely used in food products and topical and oral
pharmaceutical formulations. It is generally regarded as a nontoxic
and nonirritant material, although excessive oral consumption may
be harmful. Inhalation of alginate dust may be an irritant and has
been associated with industrially related asthma in workers
involved in alginate production. However, it appears that the cases
of asthma were linked to exposure to unprocessed seaweed dust
rather than pure alginate dust. An acceptable daily intake of
alginic acid and its ammonium, calcium, potassium, and sodium
salts was not set by the WHO because the quantities used, and the
background levels in food, did not represent a hazard to health.
LD50 (rat, IP): 1.6 g/kg
- storageAlginic acid hydrolyzes slowly at warm temperatures producing a
material with a lower molecular weight and lower dispersion
Alginic acid dispersions are susceptible to microbial spoilage on storage, which may result in some depolymerization and hence a decrease in viscosity. Dispersions should therefore be preserved with an antimicrobial preservative such as benzoic acid; potassium sorbate; sodium benzoate; sorbic acid; or paraben. Concentrations of 0.1–0.2% are usually used.
Alginic acid dispersions may be sterilized by autoclaving or filtration through a 0.22 μm filter. Autoclaving may result in a decrease in viscosity which can vary depending upon the nature of any other substances present.
Alginic acid should be stored in a well-closed container in a cool, dry place.
- Purification MethodsTo 5g of acid in 550mL water containing 2.8g KHCO3 are added 0.3mL of acetic acid and 5g potassium acetate. EtOH is added to make the solution to 25% (v/v) in EtOH, and any insoluble material is discarded. Further addition of EtOH, to 37% (v/v), precipitated alginic acid. Collect the acid and dry it in vacuo. [Pal & Schubert J Am Chem Soc 84 4384 1962.]
- IncompatibilitiesIncompatible with strong oxidizing agents; alginic acid forms insoluble salts in the presence of alkaline earth metals and group III metals with the exception of magnesium.
- Regulatory StatusGRAS listed. Accepted in Europe for use as a food additive. Included in the FDA Inactive Ingredients Database (ophthalmic preparations, oral capsules, and tablets). Included in the Canadian List of Acceptable Non-medicinal Ingredients. Included in nonparenteral medicines licensed in the UK.
Alginic acid Preparation Products And Raw materials
- BENZYL ISOCYANIDE 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE COBALT(II) ACETYLACETONATE PHENYLSELENOL Ethyl isocyanoacetate Cupric acetylacetonate Aluminum acetylacetonate TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) SALCOMINE Alginic acid Citric acid Ascoric Acid Glycine Folic acid Algin, Alginic acid sodium salt from brown algae, Sodium alginate,ALGINIC ACID SODIUM LOW VISCOSITY FROMMA CROCYSTIS,ALGINIC ACID SODIUM MEDIUM VISCOSITYFROM MACROCYST,ALGINIC ACID SODIUM SALT, 90% (LOW MOLECULAR WEIGHT),Alginic acid sodium salt, high viscosity,Alginic acid monosodium salt,ALGINIC ACID SODIUM SALT,Alginic acid sodium salt from brown algae,alginic acid sodium,ALGINIC ACID SODIUM SALT F. BROWN ALGAE, F.IMM. OF MICROORR.,Alginic acid sodium salt, very low viscosity,SODIU Ethyl 2-(Chlorosulfonyl)acetate Alginic acid 2-hydroxypropyl,Alginic acid propyleneglycol
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