LEVETIRACETAM-D6

Product NameLEVETIRACETAM-D6
CAS1133229-30-7
MFC8H14N2O2
MW170.21
EINECS
MOL FileMol File

Chemical Properties

Melting point	116-117°C
storage temp.	-20°C Freezer, Under inert atmosphere
solubility	Acetone (Slightly, Sonicated), Chloroform (Slightly), Methanol (Slightly)
form	Solid
color	White to Off-White

Usage And Synthesis

Description

Levetiracetam-d₆ is intended for use as an internal standard for the quantification of levetiracetam by GC- or LC-MS. Levetiracetam is an antiepileptic agent that binds to the synaptic vesicle protein SV2A (IC₅₀ = 1.99 μM). In vivo, levetiracetam suppresses seizures in fully kindled rats.

Uses

LevetiracetaM-d6 is the labelled (S)-enantiomer of the ethyl analog of Piracetam,it is uUsed as an anticonvulsant.

Uses

Levetiracetam-d6 is a labelled (S)-enantiomer of the ethyl analog of Piracetam (P500800), an anticonvulsant.

References

[1] BERKLEY A LYNCH. The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam.[J]. Proceedings of the National Academy of Sciences of the United States of America, 2004, 101 26: 9861-9866. DOI: 10.1073/pnas.0308208101
[2] WOLFGANG LSCHER C B. Prevention or modification of epileptogenesis after brain insults: experimental approaches and translational research.[J]. Pharmacological Reviews, 2010, 62 4: 668-700. DOI: 10.1124/pr.110.003046