Basic information Description References Safety Related Supplier
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Basic information Description References Safety Related Supplier
4-Ethylphenol Basic information
4-Ethylphenol Chemical Properties
  • Melting point:40-42 °C(lit.)
  • Boiling point:218-219 °C(lit.)
  • Density 1,011 g/cm3
  • vapor density 4.2 (vs air)
  • vapor pressure 0.13 mm Hg ( 20 °C)
  • refractive index 1.5330
  • Flash point:213 °F
  • storage temp. Store below +30°C.
  • solubility 4.9g/l
  • form Crystalline Mass or Crystals
  • pkapK1:10.0 (25°C)
  • Specific Gravity1.0123 (20℃)
  • color White to brownish
  • Water Solubility 4.9 g/L (25 ºC)
  • JECFA Number694
  • BRN 1363317
  • Stability:Stable. Incompatible with acid chlorides, acid anhydrides, oxidizing agents.
  • CAS DataBase Reference123-07-9(CAS DataBase Reference)
  • NIST Chemistry ReferencePhenol, 4-ethyl-(123-07-9)
  • EPA Substance Registry Systemp-Ethylphenol (123-07-9)
Safety Information
4-Ethylphenol Usage And Synthesis
  • Description4-Ethylphenol, often abbreviated to 4-EP, is a phenolic compound with the formula C8H10O. It is colorless or white needles with a powerful woody-phenolic and yet somewhat sweet odor and  tends to be yellow on exposure to light. It is slightly solouble in water, solouble in alcohol, ether and benzene and carbon disulfide. It is found in arabica coffee and can be produced in wine and beer by the spoilage yeast Brettanomyces. It is the starting material for the production of 4-vinylphenol and of various antioxidants and can also be used as an intermediate for pharmaceuticals and dyes.
  • References1.
  • Chemical Propertiesoff-white solid
  • Chemical Propertiesp-Ethylphenol has a powerful woody-phenolic, medicinal, yet somewhat sweet odor.
  • OccurrenceReported found in yellow passion fruit, smoked fish, lean fish, beer, cognac, rum, whiskey, cider, sherry, grape wines and coffee
  • UsesIntermediates of Liquid Crystals
  • PreparationBy catalytic reaction between phenol and ethylene or ethanol; by heating 8-chloro-3-ethylbenzene with NaOH in the presence of copper powder.
  • Aroma threshold valuesDetection: 42 to 130 ppb
  • Synthesis Reference(s)The Journal of Organic Chemistry, 14, p. 1089, 1949 DOI: 10.1021/jo01158a018
  • HazardToxic material.
  • Safety ProfilePoison by intravenous route. When heated to decomposition it emits acrid smoke and irritating vapors.
  • Purification MethodsNon-acidic impurities are removed by passing steam through a boiling solution containing 1 mole of the phenol and 1.75 moles of NaOH (as an aqueous 10% solution). The residue is cooled and acidified with 30% (v/v) H2SO4, and the free phenol is extracted into diethyl ether. The extract is washed with water, dried with CaSO4 and the ether is evaporated. The phenol is distilled at 100mm pressure through a Stedman gauze-packed column (p 11). It is further purified by fractional crystallisation by partial freezing, and by zone refining, under N2 [Biddiscombe et al. J Chem Soc 5764 1963]. Alternatively purify it via the benzoate, as for phenol. The 4-nitrophenylbenzoate has m 80o (from EtOH). [Beilstein 6 H 470, 6 III 1663, 5 IV 3020.]
4-Ethylphenol Preparation Products And Raw materials
4-Ethylphenol(123-07-9)Related Product Information
  • Company Name:Nanjing Datang Chemical Co., Ltd Gold
  • Tel:+86-25-85431992
  • Products Intro:Product Name:PEP;P-ETHYLPHENOL;(4-Hydroxyphenyl)ethane;(p-Hydroxyphenyl)ethane;1-Ethyl-4-hydroxybenzene;1-Hydroxy-4-ethylbenzene;4-ethyl-pheno;4-hydroxyphenylethane
    Purity:98% Package:200kg
  • Company Name:Powerful Chemical (Shanghai) Co., Ltd. Gold
  • Tel:18917958225
  • Products Intro:Product Name:4-Ethylphenol;p-Ethylphenol;1-Hydroxy-4-ethylbenzene ;4-Ethyl-phenol
    Purity:99 Package:200 kg/ 500g
  • Company Name:J & K SCIENTIFIC LTD.
  • Tel:400-666-7788 010-82848833-
  • Products Intro:Product Name:4-Ethylphenol
    Purity:99% Package:100G,25G,500G
  • Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
  • Tel:400-660-8290 21-61259100-
  • Products Intro:Product Name:4-Ethylphenol
    Purity:>97.0%(GC) Package:25g;500g Remarks:E0159
  • Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
  • Tel:18930552037 821-50328103-801
  • Products Intro:Product Name:4-Ethylphenol
    Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g