colorless to light yellow crystalline powder
2-(Methylthio)benzothiazole was used in trace determination of polar 1H-benzotriazoles and benzothiazoles in drinking and surface water by liquid chromatography-electrospray mass spectrometry.
2-(Methylthio)Benzothiazole could be useful for removing pollutants in drinking water.
ChEBI: An organic sulfide that is the methyl thioether of 1,3-benzothiazole-2-thiol.
2-(Methylthio)benzothiazole is the degradation product of 2-(thiocyanomethylthio)benzothiazole, a biocide used in the leather, pulp, paper and water-treatment industries.
When 2-methylthiobenzothiazole and 35S-labeled
glutathione (GSH) are incubated with rat liver
microsomes, both 35S-labeled S-(2-
benzothiazolyl)glutathione and 2-
mercaptobenzothiazole are isolated from the reaction
mixtures. Glutathione-S-transferase appears to be
involved in the S-(2- benzothiazolyl)glutathione
formation. Although sulfur is exchanged in this
pathway, the net result of this pathway which involves
oxidation of the methylthio group and GSH conjugation
is an apparent S-demethylation of the methylthio
group. Another S-demethylation pathway that does not
involve GSH conjugation also functions in vitro.
