Triphenylphosphine diiodide (Ph
3P. I
2) can be used as a reagent:
- To facilitate the conversion of alcohol, thiol, and enol functional groups into alkyl iodides via formation of alkoxyphosphonium iodide.
- To prepare β-iodo-α,β-unsaturated ketones from cyclic β-diketones in the presence of triethyl amine.
- In the synthesis of alkyl nitrates from alcohols.
- In the Beckmann rearrangement reaction to synthesize lactams from cycloalkanone oxime.
- For the preparation of aromatic and aliphatic carboxylic acid esters in the presence of N,N-dimethylaminopyridine.
Ph
3P. I
2 can also be used to reduce graphene oxide for the production of graphene nanosheets under mild and environmentally friendly conditions.
